CircMYBL2 regulates the resistance of cervical cancer cells to paclitaxel via miR-665-dependent regulation of EGFR.
Sign Up to like & getrecommendations! Published in 2021 at "Drug development research"
DOI: 10.1002/ddr.21834
Abstract: Circular RNAs are considered to be associated with cancer resistance. This study aims to investigate the function and mechanism of circMYBL2 in paclitaxel (PTX) resistance of cervical cancer (CC). The expression of circMYBL2, miR-665 and… read more here.
Keywords: egfr; mir 665; circmybl2; cancer ... See more keywords
microRNA‐665 silencing improves cardiac function in rats with heart failure through activation of the cAMP signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27987
Abstract: Heart failure (HF) is a disease with high mortality and morbidity rate. Previous studies have shown that microRNAs (miRNAs) may be implicated in the pathogenesis of HF, potentially being able to improve the cardiac function… read more here.
Keywords: signaling pathway; camp signaling; mir 665; cardiac function ... See more keywords
MicroRNA-665-3p attenuates oxygen-glucose deprivation-evoked microglial cell apoptosis and inflammatory response by inhibiting NF-κB signaling via targeting TRIM8.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106650
Abstract: Microglial inflammation induced by ischemic stroke aggravates brain damage. MicroRNAs (miRNAs) have emerged as pivotal regulators in ischemic stroke-induced inflammation in microglial cells. miR-665-3p has been reported as a critical inflammation-associated miRNA. However, whether miR-665-3p… read more here.
Keywords: inflammation microglial; ogd induced; mir 665; oxygen glucose ... See more keywords
LncRNA MIAT regulates autophagy and apoptosis of macrophage infected by Mycobacterium tuberculosis through the miR-665/ULK1 signaling axis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2021.07.023
Abstract: Accumulating lines of evidence have revealed the involvement of long non-coding RNAs (lncRNAs) in the control and elimination of invading Mycobacterium tuberculosis (Mtb) by macrophage. In this study, we sought to elucidate the role of… read more here.
Keywords: autophagy apoptosis; miat; mir 665; macrophage ... See more keywords
RNF144A-AS1 promotes the development of glioma cells by targeting miR-665/HMGA1 axis
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2021.136259
Abstract: PURPOSE Glioma is a malignant tumor in the central nervous system. Long non-coding RNA (lncRNA) RNF144A-AS1 exerts a regulatory effect in cancers, but its role in glioma remains obscure and needs to be further study.… read more here.
Keywords: glioma; hmga1; mir 665; rnf144a as1 ... See more keywords
MicroRNA-665 mediates propofol-induced cell apoptosis in human stem cell-derived neurons
Sign Up to like & getrecommendations! Published in 2019 at "Bioengineered"
DOI: 10.1080/21655979.2019.1682105
Abstract: ABSTRACT We aimed to evaluate the neurotoxicity and mechanisms of anesthetics propofol in hESC-derived neurons. Cell apoptosis in hESC-derived neurons' exposure to 4, 10 and 20 μg/mL propofol for 6 h was assessed using terminal… read more here.
Keywords: propofol induced; derived neurons; mir 665; cell apoptosis ... See more keywords
Long non-coding RNA NHEG1/hsa-miR-665/HMGB1 axis is involved in the regulation of neuroblastoma progression
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1983277
Abstract: ABSTRACT Long non-coding (lncRNA) neuroblastoma highly expressed 1 (NHEG1) has been reorganized as a prognostic factor in neuroblastoma (NB), but the molecular mechanisms in the suppression of neuroblastoma remain to be elucidated. In our study,… read more here.
Keywords: hsa mir; lncrna nheg1; mir 665; hmgb1 ... See more keywords
MicroRNA-665-3p exacerbates nonalcoholic fatty liver disease in mice
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2017698
Abstract: ABSTRACT Oxidative stress and chronic inflammation are major culprits of nonalcoholic fatty liver disease (NAFLD). MicroRNA-665-3p (miR-665-3p) is implicated in regulating inflammation and oxidative stress; however, its role and molecular basis in NAFLD remain elusive.… read more here.
Keywords: nonalcoholic fatty; inflammation; fatty liver; oxidative stress ... See more keywords
DANCR‐mediated microRNA‐665 regulates proliferation and metastasis of cervical cancer through the ERK/SMAD pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Science"
DOI: 10.1111/cas.13921
Abstract: Emerging evidence has indicated that microRNAs (miRNAs) play an important role in cervical cancer (CC). However, the role of miRNA (miR)‐665 in cervical cancer remains unclear. The aim of the present study was to investigate… read more here.
Keywords: erk smad; mir 665; cervical cancer; smad pathway ... See more keywords
Abstract 6686: Tumor suppressor miRNA-665 based serum biomarker for detecting pancreatobiliary cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6686
Abstract: Background: MicroRNA-665 (miR-665), an intracellular inhibitor of pancreatic cancer (PC) cells, might be a potential biomarker to detect pancreatobiliary cancer (PBca). We sought to determine the diagnostic ability of miR-665 as a serum biomarker for… read more here.
Keywords: biomarker; serum; validation; mir 665 ... See more keywords
Sevoflurane Inhibits Metastasis in Hepatocellular Carcinoma by Inhibiting MiR-665-Induced Activation of the ERK/MMP Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Cell Transplantation"
DOI: 10.1177/09636897221104447
Abstract: Recent evidence has indicated that inhalational anesthetics may affect the growth and malignant potential of tumor cells and ultimately influence tumor recurrence after surgery. Sevoflurane, a volatile anesthetic, is used extensively in hepatectomy. However, the… read more here.
Keywords: hepatocellular carcinoma; hcc cells; sevoflurane; mir 665 ... See more keywords