Exosomal circ_PTPRA inhibits tumorigenesis and promotes radiosensitivity in colorectal cancer by enriching the level of SMAD4 via competitively binding to miR-671-5p
Sign Up to like & getrecommendations! Published in 2022 at "Cytotechnology"
DOI: 10.1007/s10616-021-00506-y
Abstract: Accumulating evidence supports that exosomal RNAs are crucial in tumor microenvironment and may be used as diagnostic biomarkers for cancers. This study aimed to determine the role of exosomal circular RNA_protein tyrosine phosphatase receptor type… read more here.
Keywords: circ ptpra; cell; ptpra; mir 671 ... See more keywords
miR-671-5p Attenuates Neuroinflammation via Suppressing NF-κB Expression in an Acute Ischemic Stroke Model.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-021-03321-1
Abstract: This study was designed to investigate the role of miR-671-5p in in vitro and in vivo models of ischemic stroke (IS). Middle cerebral artery occlusion and reperfusion (MCAO/R) in C57BL/6 mice as well as oxygen-glucose… read more here.
Keywords: ischemic stroke; neuroinflammation via; mir 671; mir ... See more keywords
Uncovering the role of microRNA671-5p/CDCA7L/monoamine oxidase-A signaling in Helicobacter pylori mediated apoptosis in gastric epithelial cells.
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens and disease"
DOI: 10.1093/femspd/ftad006
Abstract: Helicobacter pylori is a gram-negative microaerophilic bacterium and is associated with gastrointestinal diseases ranging from peptic ulcer and gastritis to gastric cancer and mucosa-associated lymphoid tissue lymphoma. In our laboratory, the transcriptomes and miRnomes of… read more here.
Keywords: mir 671; pylori infection; infection; cdca7l ... See more keywords
Identification of Functional Single Nucleotide Polymorphisms in the Porcine SLC6A4 Gene Associated with Aggressive Behavior in Weaned Pigs after Mixing.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of animal science"
DOI: 10.1093/jas/skac131
Abstract: Variation in genes of the serotonergic system influence aggressive behavior by affecting serotonin levels in the central and cortical nervous system. SLC6A4 (serotonin transporter) is a master regulator of 5-HT signaling and involved in the… read more here.
Keywords: mir 671; behavior; functional single; porcine slc6a4 ... See more keywords
Hypoxic cancer-associated fibroblast exosomal circSTAT3 drives triple negative breast cancer stemness via miR-671-5p/NOTCH1 signaling
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-025-06794-8
Abstract: The hypoxic tumor microenvironment, particularly hypoxia-conditioned cancer-associated fibroblasts (CAFs), drives breast cancer (BC) progression and therapy resistance. However, the molecular mechanisms linking hypoxic CAFs to BC plasticity and chemoresistance remain elusive. Primary CAFs were isolated… read more here.
Keywords: hypoxic caf; cancer; circstat3; mir 671 ... See more keywords
Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Epigenetics"
DOI: 10.1186/s13148-017-0428-1
Abstract: BackgroundMicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility of… read more here.
Keywords: mir 671; hsa mir; analysis; mir ... See more keywords
miR-671-5p as a diagnostic biomarker and therapeutic target in periodontitis via THBS1 regulation
Sign Up to like & getrecommendations! Published in 2025 at "Hereditas"
DOI: 10.1186/s41065-025-00546-w
Abstract: Early diagnosis and therapeutic targeting of periodontitis remain challenging. This study aimed to investigate the clinical relevance and mechanistic role of miR-671-5p in pathogenesis of periodontitis. Clinical data and gingival crevicular fluid (GCF) samples were… read more here.
Keywords: biomarker therapeutic; diagnostic biomarker; periodontitis; target periodontitis ... See more keywords
miR-671-5p Promotes Cell Proliferation, Invasion, and Migration in Hepatocellular Carcinoma through Targeting ALDH2.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2022041749
Abstract: We explored the mechanism of acetaldehyde dehydrogenase 2 (ALDH2) in modulating cell behaviors in hepatocellular carcinoma (HCC), and provided fresh ideas for targeted treatment of HCC. The target messenger RNA (mRNA) was determined by The… read more here.
Keywords: mir 671; proliferation; hcc; aldh2 ... See more keywords
A review on the role of miR-671 in human disorders
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1077968
Abstract: miR-671 is encoded by a gene on 7q36.1 and contributes to the pathogenesis of a variety of disorders, including diverse types of cancers, atherosclerosis, ischemic stroke, liver fibrosis, osteoarthritis, Parkinson’s disease, rheumatoid arthritis, acute myocardial… read more here.
Keywords: role mir; mir 671; cancer; carcinoma ... See more keywords
Association between microRNA 671 polymorphisms and the susceptibility to soft tissue sarcomas in a Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.960269
Abstract: This study evaluated the association between the microRNA (miRNA) gene polymorphisms and the susceptibility to soft tissue sarcomas (STSs). In this case–control study, DNA was extracted from leukocytes in peripheral blood, which was collected from… read more here.
Keywords: association microrna; snps mir; mir 671; polymorphisms susceptibility ... See more keywords
Role of miRNA-671-5p in Mediating Wnt/β-Catenin-Triggered Podocyte Injury
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.784489
Abstract: Podocyte injury and proteinuria are the most common features of glomerular disease, which is the leading cause of end-stage renal failure. Hyperactivated Wnt/β-catenin signaling is closely associated with podocyte injury, but the underlying mechanisms are… read more here.
Keywords: injury; wnt catenin; podocyte injury; role ... See more keywords