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   Articles with "mir 758" as a keyword



miR-758-3p Interferes with Neuronal Apoptosis in Cerebral Ischemia–Reperfusion by Inhibiting ILK

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recommendations! Published in 2025 at "Molecular Neurobiology"

DOI: 10.1007/s12035-025-04736-5

Abstract: This study investigated the role of integrin-linked kinase (ILK) in neuronal apoptosis induced by cerebral ischemia‒reperfusion injury (CIRI) and its interaction with a circRNA (0000964) and miR-758-3p. Using in vivo and in vitro rat models,… read more here.

Keywords: neuronal apoptosis; mir 758; ilk; ciri ... See more keywords

Glucagon-like peptide-1 contributes to increases ABCA1 expression by downregulating miR-758 to regulate cholesterol homeostasis.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.02.126

Abstract: Abnormal regulation of lipid metabolism is associated with type 2 diabetes mellitus (T2DM). GLP-1 as a new treatment for T2DM, has unique effects in modulating cholesterol homeostasis. However, the mechanism of this effect is largely… read more here.

Keywords: mir 758; abca1 expression; cholesterol homeostasis; cholesterol ... See more keywords

Mir-758-5p Suppresses Glioblastoma Proliferation, Migration and Invasion by Targeting ZBTB20

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recommendations! Published in 2018 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000492545

Abstract: Background/Aims: To determine the cellular functions and clinical significance of micro-758-5p (miR-758-5p) in glioblastoma (GBM) by targeting zinc finger and BTB domain-containing protein 20 (ZBTB20). Methods: Fifty-five paired GBM tissues and adjacent normal tissues, GBM… read more here.

Keywords: mir 758; gbm; proliferation; zbtb20 ... See more keywords

The lncRNA DANCR promotes breast cancer brain metastasis by acting as a ceRNA for miR-758-3p to regulate PTGS2 expression.

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recommendations! Published in 2025 at "Acta biochimica et biophysica Sinica"

DOI: 10.3724/abbs.2025082

Abstract: Brain metastases in breast cancer patients are correlated with markedly lower survival rates than extracranial metastases, highlighting the critical necessity for identifying novel therapeutic targets. The functional involvement of differentiation antagonizing nonprotein coding RNA (DANCR)… read more here.

Keywords: breast cancer; brain; ptgs2; mir 758 ... See more keywords