Involvement of miR-770-5p in trastuzumab response in HER2 positive breast cancer cells
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DOI: 10.1371/journal.pone.0215894
Abstract: miRNAs may play effective roles in breast cancer so modulating their expression levels could have therapeutic benefits. Recent studies have found the combination of miRNA-based therapeutics with conventional drugs as promising. This study aimed to… read more here.
Keywords: trastuzumab response; mir 770; cancer cells; breast cancer ... See more keywords
MicroRNA-770-5p contributes to podocyte injury via targeting E2F3 in diabetic nephropathy
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DOI: 10.1590/1414-431x20209360
Abstract: Diabetic nephropathy (DN) has been identified as the major cause of end-stage renal disease (ESRD) in most developed countries. MicroRNA-770-5p depletion could repress high glucose (HG)-triggered apoptosis in podocytes, and downregulation of E2F transcription factor… read more here.
Keywords: mir 770; apoptosis; podocyte injury; e2f3 ... See more keywords