TGF-β2-induced circ-PRDM5 regulates migration, invasion, and EMT through the miR-92b-3p/COL1A2 pathway in human lens epithelial cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular histology"
DOI: 10.1007/s10735-021-10053-7
Abstract: CircRNA circ-PRDM5 (PR/SET domain 5) (circ-PRDM5) is overexpressed in age-related cataracts. Nevertheless, the biological role of circ-PRDM5 in posterior capsule opacities (PCO) (a common complication after cataract surgery) is unclear. Human lens epithelial cells SRA01/04… read more here.
Keywords: prdm5; mir 92b; circ prdm5; migration invasion ... See more keywords
miR-25 and miR-92b regulate insulin biosynthesis and pancreatic β-cell apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine"
DOI: 10.1007/s12020-022-03016-9
Abstract: Pancreatic β-cell failure is a central hallmark of the pathogenesis of diabetes mellitus; however, the molecular basis underlying chronic inflammation-caused β-cell failure remains unclear. This study reported here specifically assessed the association between miR-25/miR-92b family… read more here.
Keywords: mir; apoptosis; mir mir; seed ... See more keywords
Lin28B/miR-92b Promote the Proliferation, Migration, and Invasion in the Pathogenesis of Preeclampsia via the DKK1/Wnt/β-Catenin Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-019-00083-8
Abstract: Preeclampsia (PE) is a disease unique to pregnancy and one of the leading causes of maternal and neonatal morbidity and mortality. Our previous study found that Lin28b, an RNA-binding protein stem cell factor, is down-expressed… read more here.
Keywords: invasion; catenin; preeclampsia; mir 92b ... See more keywords
Circulating MicroRNA-92b-3p as a Novel Biomarker for Monitoring of Synovial Sarcoma
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12660-5
Abstract: The lack of useful biomarkers is a crucial problem for patients with soft tissue sarcomas (STSs). Emerging evidence has suggested that circulating microRNAs (miRNAs) in body fluids have novel impact as biomarkers for patients with… read more here.
Keywords: microrna 92b; circulating microrna; serum mir; synovial sarcoma ... See more keywords
Circulating miR-92b and miR-375 for monitoring the chemoresistance and prognosis of small cell lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-69615-6
Abstract: miRNAs have been reported to be stably detectable in plasma and to function as potent biomarkers in multiple cancers. The study aimed to evaluate the expression of candidate circulating miRNAs in patients with small cell… read more here.
Keywords: mir; cell lung; mir 375; 92b mir ... See more keywords
Circulating exosomal miR‐92b: Its role for cancer immunoediting and clinical value for prediction of posttransplant hepatocellular carcinoma recurrence
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Transplantation"
DOI: 10.1111/ajt.15490
Abstract: A recurrence of hepatocellular carcinoma (HCC) after living donor liver transplantation (LDLT) is one of the major concerns reflecting the higher mortality of HCC. This study aimed to explore the impact of circulating exosomes on… read more here.
Keywords: recurrence; value; cancer; mir 92b ... See more keywords
Foxo1‐induced miR‐92b down‐regulation promotes blood‐brain barrier damage after ischaemic stroke by targeting NOX4
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16537
Abstract: The blood‐brain barrier (BBB) damage is a momentous pathological process of ischaemic stroke. NADPH oxidases 4 (NOX4) boosts BBB damage after ischaemic stroke and its expression can be influenced by microRNAs. This study aimed to… read more here.
Keywords: mir 92b; expression; ischaemic stroke; damage ischaemic ... See more keywords
MiR‐92b‐3p regulates oxygen and glucose deprivation–reperfusion‐mediated apoptosis and inflammation by targeting TRAF3 in PC12 cells
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Physiology"
DOI: 10.1113/ep088708
Abstract: What is the central question of this study? MiR‐92b‐3p was found to be reduced in a rat model of middle cerebral artery occlusion: what are the functions of miR‐92b‐3p in oxygen and glucose deprivation–reperfusion (OGD/R)?… read more here.
Keywords: glucose deprivation; oxygen glucose; mir 92b; targeting traf3 ... See more keywords
miR-92b-3p Exerts Neuroprotective Effects on Ischemia/Reperfusion-Induced Cerebral Injury via Targeting NOX4 in a Rat Model
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3494262
Abstract: The necessity to increase the efficiency of organ preservation has pushed researchers to consider the mechanisms to minimize cerebral ischemia/reperfusion (I/R) injury. Hence, we evaluated the role of the miR-92b-3p/NOX4 pathway in cerebral I/R injury.… read more here.
Keywords: cerebral injury; model; ischemia reperfusion; injury ... See more keywords
Abstract 2538: MiR-92b targets FBXW7 in GBM cells
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2538
Abstract: MicroRNA (miRNA) dysregulation plays a central role in the initiation, progression, and drug resistance of virtually all cancer types. MiRNA-based therapies are a promising therapeutic modality against most malignancies. MiR-92b is aberrantly abundant in glioblastoma… read more here.
Keywords: 92b targets; mir 92b; cancer; gbm cells ... See more keywords
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702221095456
Abstract: Vascular calcification (VC) is the most widespread pathological change in diseases of the vascular system. However, we do not have a good understanding of the molecular mechanisms and effective therapeutic approaches for VC. Curcumin (CUR)… read more here.
Keywords: calcification; attenuates vascular; vascular calcification; klf4 ... See more keywords