Abstract 15541: Novel Molecular Entity for Effective Cardiac Regeneration: 5’ppp Microrna Induces Reprogramming and Accelerates Cardiomyocyte Maturation
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DOI: 10.1161/circ.142.suppl_3.15541
Abstract: We have shown that miR combo directly reprograms fibroblasts into cardiomyocytes. However, both in vitro and in vivo, the generated cardiomyocytes are immature. Recently, we discovered that cardiomyocyte maturation is enhanced by NFkB activation. While… read more here.
Keywords: maturation; molecular entity; mir combo; cardiomyocyte maturation ... See more keywords