Controlled RISC loading efficiency of miR168 defined by miRNA duplex structure adjusts ARGONAUTE1 homeostasis
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DOI: 10.1093/nar/gkab1138
Abstract: Abstract Micro RNAs (miRNAs) are processed from precursor RNA molecules with precisely defined secondary stem-loop structures. ARGONAUTE1 (AGO1) is the main executor component of miRNA pathway and its expression is controlled via the auto-regulatory feedback… read more here.
Keywords: ago1 loading; structure; mirna duplex; mir168 ... See more keywords