The expression of MIR17HG protein as a potential therapeutic target in meningioma.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.02.039
Abstract: BACKGROUND MIR17 host gene (MIR17HG) is a potential therapeutic target for some cancer types. The aim of this study was to assess MIR17HG protein levels in patients with meningioma which were not reported previously in… read more here.
Keywords: grade; mir17hg protein; meningioma; potential therapeutic ... See more keywords
MIR17HG polymorphisms contribute to high-altitude pulmonary edema susceptibility in the Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-06944-8
Abstract: High-altitude pulmonary edema (HAPE) is a common acute altitude sickness. This study was designed to investigate the effect of MIR17HG polymorphisms on HAPE risk in the Chinese population. The Agena MassARRAY platform was used to… read more here.
Keywords: risk; mir17hg; chinese population; mir17hg polymorphisms ... See more keywords
A positive feedback loop of SIRT1 and miR17HG promotes the repair of DNA double-stranded breaks
Sign Up to like & getrecommendations! Published in 2019 at "Cell Cycle"
DOI: 10.1080/15384101.2019.1641388
Abstract: ABSTRACT Long noncoding RNAs (lncRNAs) have emerged as critical regulators for gene expression in multiple levels and thus are involved in various physiological and pathological processes. Sirtuin 1 (SIRT1) has been established to exert key… read more here.
Keywords: sirt1; positive feedback; sirt1 mir17hg; repair dna ... See more keywords
LncRNA miR-17-92a-1 cluster host gene (MIR17HG) promotes neuronal damage and microglial activation by targeting the microRNA-153-3p/alpha-synuclein axis in Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2033409
Abstract: ABSTRACT Long noncoding RNAs (lncRNAs) have been regarded as modulators of neurodegenerative diseases. Here, we addressed the role of lncRNA miR-17-92a-1 cluster host gene (MIR17HG) in Parkinson’s disease (PD). C57BL/6 mice and SH-SY5Y cells were… read more here.
Keywords: mir 153; mir 92a; alpha synuclein; 92a cluster ... See more keywords
LncRNA-MIR17HG mediated upregulation of miR-17 and miR-18a promotes colon cancer progression via activating Wnt/β-catenin signaling
Sign Up to like & getrecommendations! Published in 2019 at "Translational cancer research"
DOI: 10.21037/30055
Abstract: Background: Long non-coding RNA MIR17HG (miR-17-92 cluster host gene lncRNA) is synthesized from miR-17-92 cluster host gene due to pre-miRNA processing, and is referred as miRNA-host gene lncRNA (lnc-miRHG). Until now, the biologic function of… read more here.
Keywords: mir; colon cancer; cancer; mir17hg ... See more keywords