Macrophage Reprogramming with Anti‐miR223‐Loaded Artificial Protocells Enhances In Vivo Cancer Therapeutic Potential (Adv. Sci. 35/2022)
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DOI: 10.1002/advs.202202717
Abstract: Several immune cell‐expressed miRNAs (miRs) are associated with altered prognostic outcome in cancer patients, suggesting that they may be potential targets for development of cancer therapies. Here, translucent zebrafish (Danio rerio) is utilized to demonstrate… read more here.
Keywords: macrophage reprogramming; anti mir223; mir223; mir223 loaded ... See more keywords
Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1
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DOI: 10.1080/15548627.2018.1522467
Abstract: ABSTRACT Microglia are innate immune cells in the central nervous system (CNS), that supplies neurons with key factors for executing autophagosomal/lysosomal functions. Macroautophagy/autophagy is a cellular catabolic process that maintains cell balance in response to… read more here.
Keywords: atg16l1; cns inflammation; mir223; autophagy related ... See more keywords
MicroRNA-223: a key regulator of liver tumour microenvironment
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DOI: 10.1136/gutjnl-2022-329322
Abstract: Hepatocellular carcinoma (HCC) is the fourth leading cause of cancerrelated deaths worldwide with few effective drug treatments. Recent combination therapies inhibiting immune checkpoints and angiogenesis showed better overall and progressionfree survival outcomes than the protein… read more here.
Keywords: hcc; expression; pd1 pdl1; mir223 ... See more keywords