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Sepsis Encephalopathy Is Partly Mediated by miR370-3p-Induced Mitochondrial Injury but Attenuated by BAM15 in Cecal Ligation and Puncture Sepsis Male Mice

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23105445

Abstract: BAM15 (a mitochondrial uncoupling agent) was tested on cecal ligation and puncture (CLP) sepsis mice with in vitro experiments. BAM15 attenuated sepsis as indicated by survival, organ histology (kidneys and livers), spleen apoptosis (activated caspase… read more here.

Keywords: sepsis; ligation puncture; brain; injury ... See more keywords