Mirabegron improves the irritative symptoms caused by BCG immunotherapy after transurethral resection of bladder tumors.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer medicine"
DOI: 10.1002/cam4.4278
Abstract: BACKGROUND This study aims to explore the efficacy and safety of mirabegron in treating irritative symptoms induced by intravesical immunotherapy with Bacillus Calmette-Guerin (BCG) after transurethral resection of bladder tumors (TURBT). METHODS A total of… read more here.
Keywords: irritative symptoms; bcg perfusion; bladder; group ... See more keywords
Continuous administration of mirabegron has advantages in inhibition of central sensitization compared with short‐term treatment cessation in a mouse model of overactive bladder
Sign Up to like & getrecommendations! Published in 2022 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24956
Abstract: There is no clear pathophysiologic evidence determining how long overactive bladder (OAB) medication should be continued. We, therefore, investigated the effect of mirabegron using cessation (CES) or continuation (CON) treatment in an OAB animal model. read more here.
Keywords: bladder; cessation; overactive bladder; model ... See more keywords
Adjunction of tamsulosin or mirabegron before semi-rigid ureterolithotripsy improves outcomes: prospective, randomized single-blind study
Sign Up to like & getrecommendations! Published in 2019 at "International Urology and Nephrology"
DOI: 10.1007/s11255-019-02142-0
Abstract: ObjectiveTo evaluate efficiency and safety of adjunct tamsulosin and mirabegron therapy before semi-rigid ureteroscopy for ureteral stones.Materials and methodsIn this prospective, randomized, single-blind and multicentric study, participants were randomized into three groups. Group 1 was… read more here.
Keywords: tamsulosin mirabegron; mirabegron; semi rigid; group ... See more keywords
Efficacy and Safety of Mirabegron in Men with Overactive Bladder Symptoms and Benign Prostatic Hyperplasia
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DOI: 10.1007/s11934-020-01017-7
Abstract: Purpose of Review To review the efficacy and safety of mirabegron in men with overactive bladder (OAB) and benign prostatic hyperplasia (BPH). Recent Findings Numerous studies have shown mirabegron to be efficacious and safe in… read more here.
Keywords: efficacy safety; men overactive; safety mirabegron; overactive bladder ... See more keywords
Mirabegron, a &bgr;3‐adrenoceptor agonist reduced platelet aggregation through cyclic adenosine monophosphate accumulation
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.04.010
Abstract: &NA; Mirabegron is a &bgr;3‐adrenoceptor agonist and released on the marked for the treatment of overactive bladder. Because mirabegron is the only &bgr;3‐adrenoceptor agonist available and substances that increase the levels of cyclic adenosine monophosphate… read more here.
Keywords: platelet aggregation; mirabegron; bgr adrenoceptor;
Long-term Safety and Efficacy of Mirabegron and Solifenacin in Combination Compared with Monotherapy in Patients with Overactive Bladder: A Randomised, Multicentre Phase 3 Study (SYNERGY II).
Sign Up to like & getrecommendations! Published in 2018 at "European urology"
DOI: 10.1016/j.eururo.2018.05.005
Abstract: BACKGROUND The long-term potential of solifenacin and mirabegron combination treatment for patients with overactive bladder (OAB) has not been previously assessed. OBJECTIVES To evaluate the safety and efficacy of solifenacin succinate 5mg plus mirabegron 50mg… read more here.
Keywords: combination; solifenacin; treatment; safety ... See more keywords
Safety and Efficacy of Mirabegron: Analysis of a Large Integrated Clinical Trial Database of Patients with Overactive Bladder Receiving Mirabegron, Antimuscarinics, or Placebo.
Sign Up to like & getrecommendations! Published in 2019 at "European urology"
DOI: 10.1016/j.eururo.2019.09.024
Abstract: BACKGROUND Mirabegron, a β3-adrenoreceptor agonist, is an alternative drug to antimuscarinics for overactive bladder (OAB) symptoms. OBJECTIVE To summarise safety and efficacy reporting of mirabegron treatment for OAB symptoms. DESIGN, SETTING, AND PARTICIPANTS Pooled data… read more here.
Keywords: overactive bladder; bladder; safety; treatment ... See more keywords
Validation of LC–MS/MS methods for the determination of mirabegron and eight metabolites in human plasma in a paediatric population
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2019.02.007
Abstract: HighlightsThree analytical methods for mirabegron and metabolites in human plasma validated.Assays miniaturized for paediatric population by using 96‐well plate technology.Methodology utilized a more sensitive mass spectrometer than previously.Reduction in both assay volume and/or assay sensitivity… read more here.
Keywords: human plasma; mirabegron eight; metabolites human; mirabegron ... See more keywords
Effectiveness and Tolerability of Mirabegron in Children with Overactive Bladder: A Retrospective Pilot Study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2019.10.044
Abstract: AIMS Mirabegron has promising results for OAB symptoms in adults, although the potential for cardiovascular side effects has caused concern. Efficacy and tolerability in children have not been extensively studied. Effectiveness, tolerability, and side effects… read more here.
Keywords: effectiveness tolerability; tolerability; tolerability mirabegron; mirabegron ... See more keywords
Mirabegron versus Placebo Add-on Therapy in Men with Overactive Bladder Symptoms Receiving Tamsulosin for Underlying Benign Prostatic Hyperplasia: a Safety Analysis from the Randomized, Phase 4 PLUS Study.
Sign Up to like & getrecommendations! Published in 2020 at "Urology"
DOI: 10.1016/j.urology.2020.09.040
Abstract: OBJECTIVES To analyze the safety of mirabegron add-on therapy in men with overactive bladder symptoms concurrently receiving tamsulosin for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). METHODS The Phase 4 PLUS… read more here.
Keywords: add therapy; safety; mirabegron; teaes ... See more keywords
Beta3-adrenergic stimulation restores endothelial mitochondrial dynamics and prevents pulmonary arterial hypertension
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DOI: 10.1093/ehjci/ehaa946.3808
Abstract: Endothelial dysfunction is one of the most important hallmarks of pulmonary arterial hypertension (PAH). This leads to anomalous production of vasoactive mediators that are responsible for a higher vascular tone and a subsequent increase in… read more here.
Keywords: arterial hypertension; effect mirabegron; pulmonary arterial; mirabegron ... See more keywords