Articles with "mirabilis" as a keyword



Identification of small molecule compounds active against Staphylococcus aureus and Proteus mirabilis.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.10.189

Abstract: Staphylococcus aureus is a human pathogen rapidly becoming a serious health problem due to ease of acquiring antibiotic resistance. To help identify potential new drug candidates effective against the pathogen, a small focused library was… read more here.

Keywords: staphylococcus aureus; small molecule; aureus; mirabilis ... See more keywords

Association of blaNDM-1 with blaKPC-2 and aminoglycoside-modifying enzymes genes among Klebsiella pneumoniae, Proteus mirabilis and Serratia marcescens clinical isolates in Brazil.

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Published in 2019 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2019.08.026

Abstract: OBJECTIVE Carbapenemase producingEnterobacterales are often involved in healthcare-associated infections worldwide. Therefore, the objective of this study was to investigate the frequency of the main genes for carbapenemases, methylases, aminoglycoside-modifying enzymes (AMEs), and mcr gene, as… read more here.

Keywords: blandm blakpc; modifying enzymes; aminoglycoside modifying; mirabilis ... See more keywords
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Molecular Characterization of β-Lactam Resistance and Antimicrobial Susceptibility to Possible Therapeutic Options of AmpC-Producing Multidrug-Resistant Proteus mirabilis in a University Hospital of Split, Croatia.

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Published in 2020 at "Microbial drug resistance"

DOI: 10.1089/mdr.2020.0002

Abstract: This study was performed to elucidate genetic relatedness and molecular resistance mechanisms of AmpC-producing multidrug-resistant Proteus mirabilis isolates in University Hospital of Split (UHS), and define efficient antibiotics in vitro. A total of 100 nonrepeated,… read more here.

Keywords: hospital; ampc producing; resistance; multidrug resistant ... See more keywords

Establishment of epidemiological cut-off values of etimicin: a new fourth-generation aminoglycoside, against Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus

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Published in 2024 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dkae414

Abstract: Abstract Objective To determine the epidemiological cut-off (ECOFF) values of etimicin against Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus. Methods We selected 1500 isolates from five hospitals throughout five… read more here.

Keywords: escherichia coli; aeruginosa; baumannii; epidemiological cut ... See more keywords

Identification of mechanisms modulating chlorhexidine and octenidine susceptibility in Proteus mirabilis.

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Published in 2024 at "Journal of applied microbiology"

DOI: 10.1093/jambio/lxae173

Abstract: AIMS We aimed to identify mechanisms underlying the tolerance of P. mirabilis-a common cause of catheter associated urinary tract infection-to the clinically used biocides chlorhexidine (CHD) and octenidine (OCT). METHODS AND RESULTS We adapted three… read more here.

Keywords: susceptibility; modulating chlorhexidine; chd; identification mechanisms ... See more keywords

Proteus mirabilis UreR coordinates cellular functions required for urease activity

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Published in 2024 at "Journal of Bacteriology"

DOI: 10.1128/jb.00031-24

Abstract: ABSTRACT A hallmark of Proteus mirabilis infection of the urinary tract is the formation of stones. The ability to induce urinary stone formation requires urease, a nickel metalloenzyme that hydrolyzes urea. This reaction produces ammonia… read more here.

Keywords: proteus mirabilis; urease; regulation; urer ... See more keywords

Interaction of the SXT/R391 element ICEPmiJpn1 with its natural host Proteus mirabilis

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Published in 2025 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.00339-25

Abstract: ABSTRACT Integrative and conjugative elements (ICEs) of the SXT/R391 family are mobile genetic elements that integrate into the bacterial host chromosome and can be transferred horizontally, spreading antimicrobial resistance genes. Our study aimed to evaluate… read more here.

Keywords: host proteus; host; element; natural host ... See more keywords

Decoding Proteus mirabilis biofilms: expression of selected virulence genes and association with antibiotic resistance

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Published in 2025 at "BMC Microbiology"

DOI: 10.1186/s12866-025-04212-z

Abstract: Proteus mirabilis is a uropathogens with a strong ability to form resilient crystalline biofilms, particularly on urinary catheters, contributing to its persistence and antibiotic resistance. As biofilm-driven virulence is key in complicated urinary tract infections,… read more here.

Keywords: resistance; virulence; non urine; expression ... See more keywords

Determining the cytotoxicity of the Minimum Inhibitory Concentration (MIC) of silver and zinc oxide nanoparticles in ESBL and carbapenemase producing Proteus mirabilis isolated from clinical samples in Shiraz, Southwest Iran

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Published in 2024 at "BMC Research Notes"

DOI: 10.1186/s13104-023-06402-2

Abstract: Objective Proteus mirabilis is related to serious infections. The present study was designed to investigate the minimum inhibitory concentration (MIC) of silver nanoparticles (AgNPs) and zinc oxide nanoparticles (ZnONPs) and cytotoxicity among P. mirabilis isolates… read more here.

Keywords: cytotoxicity; proteus mirabilis; inhibitory concentration; minimum inhibitory ... See more keywords

Genome sequencing and analysis of the first spontaneous Nanosilver resistant bacterium Proteus mirabilis strain SCDR1

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Published in 2017 at "Antimicrobial Resistance and Infection Control"

DOI: 10.1186/s13756-017-0277-x

Abstract: BackgroundP. mirabilis is a common uropathogenic bacterium that can cause major complications in patients with long-standing indwelling catheters or patients with urinary tract anomalies. In addition, P. mirabilis is a common cause of chronic osteomyelitis… read more here.

Keywords: resistance; scdr1 genome; mirabilis scdr1; mirabilis ... See more keywords

Distribution of antimicrobial resistance and virulence markers in chicken originated Proteus mirabilis isolates.

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Published in 2024 at "Acta veterinaria Hungarica"

DOI: 10.1556/004.2023.00990

Abstract: Proteus mirabilis is a common enteric bacterium in livestock and humans. The increase and spread of the antimicrobial resistant P. mirabilis is considered alarming worldwide. Transmission mainly occurs through consumption of contaminated poultry products. We… read more here.

Keywords: virulence markers; virulence; proteus mirabilis; antimicrobial resistance ... See more keywords