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   Articles with "mirna 137" as a keyword



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Gold nanourchin enhances detection of Alzheimer's disease biomarker “miRNA‐137” on dual electrode sensing surface

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recommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"

DOI: 10.1002/bab.2306

Abstract: Diagnosis of Alzheimer's disease (AD) is a complex task, and at present, neuroimaging such as magnetic resonance imaging and positron emission tomography is commonly used for the diagnosis of AD. This research work developed a… read more here.

Keywords: biomarker mirna; mirna 137; alzheimer disease; surface ... See more keywords
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Aberrant expression of the sFRP and WIF1 genes in invasive non-functioning pituitary adenomas

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recommendations! Published in 2018 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2018.03.005

Abstract: Non-functioning pituitary adenomas (NFPAs) are the most common pituitary tumors and mainly invade the sphenoid, cavernous sinus or dura mate. Aberrant regulation of the Wnt signaling pathway plays an important role in tumorigenesis. This study… read more here.

Keywords: wif1; non functioning; group; mirna 137 ... See more keywords
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Overexpression of miRNA-137 in the brain suppresses seizure activity and neuronal excitability: A new potential therapeutic strategy for epilepsy

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recommendations! Published in 2018 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2018.06.010

Abstract: ABSTRACT miRNA‐137 is an extremely abundant miRNA in the central nervous system and is thought to be closely related to synaptic plasticity. Here, we report a previously unrecognized role of miRNA‐137 in epilepsy. The expression… read more here.

Keywords: epilepsy; latency; overexpression mirna; mirna 137 ... See more keywords
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The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio

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recommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2112225119

Abstract: Significance The hypocretin (Hcrt, also known as orexin) neuropeptides regulate sleep and wake stability, and disturbances of Hcrt can lead to sleep disorders. MicroRNAs (miRNAs) are short noncoding RNAs that fine-tune protein expression levels, and… read more here.

Keywords: sleep wake; conserved mirna; mirna 137; mir 137 ... See more keywords
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Graphene Oxide-Gold Star Construct on Triangular Electrodes for Alzheimer's Disease Identification

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recommendations! Published in 2021 at "Journal of Analytical Methods in Chemistry"

DOI: 10.1155/2021/6661799

Abstract: Nanotechnology is playing a major role in the field of medical diagnosis, in particular with the biosensor and bioimaging. It improves the performance of the desired system dramatically by displaying higher selectivity and sensitivity. Carbon… read more here.

Keywords: graphene oxide; alzheimer disease; triangular electrodes; mirna 137 ... See more keywords