MiRNA-138-5p: A strong tumor suppressor targeting PD-L-1 inhibits proliferation and motility of breast cancer cells and induces apoptosis.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.173933
Abstract: MicroRNAs are important regulators in multiple cellular processes and are closely related to a variety of cancers including breast cancer (BC). Immunotherapy using different methods such as modulating immune check points has been known as… read more here.
Keywords: mirna 138; apoptosis; breast cancer; expression ... See more keywords
MicroRNA-138 Regulates Spinal Cord Development by Activating the Shh in Fetal Rats
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Neurosurgery"
DOI: 10.1159/000527587
Abstract: Introduction: Dysregulation of spinal cord development can lead to serious neuronal damage and dysfunction, causing significant health problems in newborns. MiRNA-138 appears to be crucial for proliferation, differentiation, and apoptosis of cells. However, the regulation… read more here.
Keywords: fetal rats; mirna 138; cord development; spinal cord ... See more keywords
Effect of intrathecal injection of miRNA-138 on neuropathic pain in rats undergoing partial sciatic nerve ligation and its underlying mechanism.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of palliative medicine"
DOI: 10.21037/apm-21-669
Abstract: BACKGROUND microRNA-138 (miRNA-138) might have a promising therapeutic effect in the Neuropathic pain (NP). We aim to investigate the effects of miRNA-138 on NP and explore its underlying mechanism. METHODS we performed a partial sciatic… read more here.
Keywords: mirna 138; mechanism; intrathecal injection; effect ... See more keywords