MicroRNA-143 Sensitizes Cervical Cancer Cells to Cisplatin: a Promising Anticancer Combination Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00479-5
Abstract: Cisplatin-based chemotherapy is commonly used for cervical cancer treatment. However, the development of chemoresistance is considered the main obstacle to the effectiveness of this therapeutic agent. MicroRNAs are illustrated to play a major role in… read more here.
Keywords: combination; cisplatin; cervical cancer; mirna 143 ... See more keywords
Epigenetic silencing of miRNA-143 regulates apoptosis by targeting BCL2 in human intervertebral disc degeneration.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2017.07.043
Abstract: Accumulating evidence indicates that microRNAs can regulate the apoptosis of various cells. Apoptosis of nucleus pulposus cells plays an important role in the progression of intervertebral disc degeneration. The aim of this study is to… read more here.
Keywords: disc; intervertebral disc; mirna 143; bcl2 ... See more keywords
The miRNA‐143‐3p–Sox6–Myh7 pathway is altered in obesogenic diet‐induced cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Physiology"
DOI: 10.1113/ep090315
Abstract: What is the central question of this study? What is the effect of an obesogenic diet on the expression of microRNAs (miRNAs) involved in cardiac hypertrophy in female mice? What is the main finding and… read more here.
Keywords: hypertrophy; 143 sox6; cardiac hypertrophy; obesogenic diet ... See more keywords
In vitro elimination of EL4 cancer cells from spermatogonia stem cells by miRNA-143- and 206-loaded folic acid conjugated PLGA nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2021-0210
Abstract: Aim: MiRNA's-143 and -206 are powerful apoptotic regulators in cancer cells. This study aimed to use miRNA-143- and 206-loaded poly(lactic-co-glycolic) acid (PLGA) nanoparticles conjugated with folic acid to induce apoptosis in the EL4 cancer cells. Materials… read more here.
Keywords: 143 206; acid; mirna 143; cancer cells ... See more keywords
MicroRNA-143 regulates cell migration and invasion by targeting GOLM1 in cervical cancer
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2018.9441
Abstract: Accumulated research has revealed that the abnormal expression of microRNAs play a crucial role in tumorigenesis, potentially serving as therapeutic biomarkers in multiple tumors including cervical cancer. However, the expression level, biological role and the… read more here.
Keywords: cervical cancer; targeting golm1; expression; mirna 143 ... See more keywords