Long noncoding RNA UCA1 promotes chondrogenic differentiation of human bone marrow mesenchymal stem cells via miRNA-145-5p/SMAD5 and miRNA-124-3p/SMAD4 axis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.140
Abstract: Long noncoding RNA (lncRNAs) UCA1 has been known to be critical for the chondrogenic differentiation of marrow mesenchymal stem cells (MSCs). In this study, we explore the effects and mechanisms of UCA1 on the promotion… read more here.
Keywords: mirna 124; mirna; mirna 145; chondrogenic differentiation ... See more keywords
MiRNA-145-5p expression and prospective molecular mechanisms in the metastasis of prostate cancer.
Sign Up to like & getrecommendations! Published in 2021 at "IET systems biology"
DOI: 10.1049/syb2.12011
Abstract: The clinicopathological implication and prospective molecular mechanisms of miRNA-145-5p in the metastasis of prostate cancer (PCa) stand unclear. Herein, it is found that miRNA-145-5p expression was remarkably reduced in 131 cases of metastatic PCa than… read more here.
Keywords: mirna 145; metastasis; pca; metastatic pca ... See more keywords
The potential value of microRNA-145 for predicting prognosis in patients with ovarian cancer
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000026922
Abstract: Abstract Background: As an anticancer gene, microRNA-145 (miRNA-145) inhibits the growth, migration, and invasion of cancer cells, and inhibits tumorigenesis by targeting various genes that are abnormally expressed in tumors. However, whether miRNA-145 can be… read more here.
Keywords: ovarian cancer; prognosis; database; cancer ... See more keywords
Pristimerin improve renal fibrosis by regulating miRNA-145-5p in vitro and vivo study
Sign Up to like & getrecommendations! Published in 2021 at "Food Science and Technology International"
DOI: 10.1590/fst.79021
Abstract: Abstract Pristimerin (Pri) was a kind of extraction from natural plant, and it has anti- inflammation effects in previous studies, however, it has been unclear that Pri’s effect in renal fibrosis treatment. The purpose of… read more here.
Keywords: pristimerin; improve renal; fibrosis; renal fibrosis ... See more keywords
Association of miRNA-145 Single Nucleotide Polymorphisms in Abdominal Aortic Aneurysms
Sign Up to like & getrecommendations! Published in 2022 at "In Vivo"
DOI: 10.21873/invivo.12810
Abstract: Background/Aim: MicroRNAs (miRNAs) are non-coding RNA molecules that exert post-transcriptional gene expression regulation in response to cellular or environmental changes. Genetic variation affects their synthesis and cellular actions, and single nucleotide polymorphisms (SNPs) are one… read more here.
Keywords: mirna 145; nucleotide polymorphisms; abdominal aortic; single nucleotide ... See more keywords
microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.988794
Abstract: Objective To investigate the effects of miRNA-145-5p on the tumor development and progression of prostate cancer (Pca) bone metastasis. Methods Levels of miRNA-145-5p were assessed by real-time quantitative PCR in PC3 (bone metastatic Pca cells),… read more here.
Keywords: mirna 145; prostate cancer; bone; bone metastatic ... See more keywords
CSDR Coupling with Exo III for Ultrasensitive Electrochemistry Determination of miR-145
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28052208
Abstract: Recently, miRNAs have become a promising biomarker for disease diagnostics. miRNA-145 is closely related to strokes. The accuracy determination of miRNA-145 (miR-145) in stroke patients still remains challenging due to its heterogeneity and low abundance,… read more here.
Keywords: mirna 145; exo iii; electrochemistry; determination ... See more keywords
Design of a Sensitive and Selective Electrochemical Aptasensor for the Determination of the Complementary cDNA of miRNA-145 Based on the Intercalation and Electrochemical Reduction of Doxorubicin.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of AOAC International"
DOI: 10.5740/jaoacint.16-0302
Abstract: The aim of this research was the determination of a microRNA (miRNA) using a DNA electrochemical aptasensor. In this biosensor, the complementary complementary DNA (cDNA) of miRNA-145 (a sense RNA transcript) was the target strand… read more here.
Keywords: aptasensor; target; electrochemical aptasensor; mirna 145 ... See more keywords