Association between miRNA‐146a rs2910164 (G/C) polymorphism with the susceptibility to chronic HBV infection and spontaneous viral clearance in an Iranian population
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25394
Abstract: Hepatitis B virus (HBV) infection is one of the clinical dilemmas in chronic liver diseases. MicroRNAs (miRNAs) are small noncoding RNA molecules that play an important role in the pathogenesis of liver diseases and single… read more here.
Keywords: hbv; mirna 146a; rs2910164 polymorphism; 146a rs2910164 ... See more keywords
TargetScore used to reveal potential targets of miRNA203 and miRNA-146a in psoriasis by integrating microRNA overexpression and microarray data
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000012671
Abstract: Objective: Systematic tracking of microRNA (miRNA) targets remains a challenge. In our work, we aimed to use TargetScore to investigate the potential targets of miRNA203 and miRNA-146a in psoriasis by integrating miRNA overexpression information and… read more here.
Keywords: 146a psoriasis; mirna 203; mirna203 mirna; potential targets ... See more keywords
The Periodontal-Cardiovascular alliance: Evaluation of miRNA-146a in subgingival plaque samples of chronic periodontitis patients with and without coronary heart disease.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of investigative and clinical dentistry"
DOI: 10.1111/jicd.12442
Abstract: AIM To quantify the levels of miRNA-146a in subgingival plaque samples, and correlate with periodontal and cardiac parameters, in chronic periodontitis patients with and without coronary heart disease. METHODS The study involved 90 subjects; 30 patients… read more here.
Keywords: heart disease; mirna 146a; coronary heart; chronic periodontitis ... See more keywords
Papain ameliorates monocyte-platelet aggregate formation-mediated inflammatory responses in monocytes by upregulating miRNA-146a transcription
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DOI: 10.1371/journal.pone.0278059
Abstract: Background MicroRNA-146a (miRNA-146a) is a nuclear factor κB (NF-κB)-inducible and inflammation-sensitive miRNA, while papain elicits anti-inflammatory effects by inhibiting monocyte-platelet aggregate (MPA)-mediated NF-κB pathway activation in monocytes. This study aimed to demonstrate the underlying effects… read more here.
Keywords: papain; expression; formation; 146a transcription ... See more keywords
Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice.
Sign Up to like & getrecommendations! Published in 2017 at "Anticancer research"
DOI: 10.21873/anticanres.11644
Abstract: BACKGROUND/AIM Human papillomavirus type 16 (HPV16) induces various types of cancer in several locations. Microenvironmental microRNAs (miRNAs) such as miRNA-146a and miRNA-150 regulate cancer-associated inflammation and are involved in HPV-induced carcinogenesis. We studied the effects… read more here.
Keywords: regulation mirna; mirna 146a; 146a mirna; hpv16 mice ... See more keywords
Dysregulation of miRNA-146a contributes to the development of lupus nephritis via targeting of TRAF6.
Sign Up to like & getrecommendations! Published in 2017 at "Personalized medicine"
DOI: 10.2217/pme-2016-0065
Abstract: AIM The objective of this study was to identify the association between genotypes of miR-146a rs2910164 and expression of TRAF6 as well as the risk of lupus nephritis (LN). RESULTS A total of 567 systemic… read more here.
Keywords: 146a contributes; mir 146a; lupus nephritis; mirna 146a ... See more keywords
MicroRNA-146a-5p induces cell cycle arrest and enhances apoptosis in gastric cancer via targeting CDC14A
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1181628
Abstract: Objective: The present study was designed to investigate the expression of miRNA-146a-5p in gastric cancer (GC) tissues and the paired nonmalignant counterparts, to explore the influences of miRNA-146a-5p on the cell biological behavior of MKN-28… read more here.
Keywords: cell; cell cycle; gastric cancer; mirna 146a ... See more keywords
Analysis of Rare Alleles of miRNA-146a (rs2910164) and miRNA-34b/c (rs4938723) as a Prognostic Marker in Thyroid Cancer in Pakistani Population
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DOI: 10.3390/diagnostics12102495
Abstract: Background: Rationale: The miRNAs are short non-coding functional RNAs that are involved in the regulation of transcriptomes. It was found that human miRNA-146a and miRNA34b/c are important microRNAs and are functioning either as onco-miRNAs, or… read more here.
Keywords: rs4938723; thyroid cancer; rs2910164; mirna 146a ... See more keywords