Expression of miRNA-223 and NLRP3 gene in IgA patients and intervention of traditional Chinese medicine
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DOI: 10.1016/j.sjbs.2020.04.034
Abstract: Objective The purpose of this study was to investigate the expression of miRNA-223 and NLRP3 in IgA patients and the intervention of traditional Chinese medicine (TCM), so as to realize the basic pathological changes of… read more here.
Keywords: medicine; mirna 223; 223 nlrp3; iga patients ... See more keywords
Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology
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DOI: 10.1128/mbio.03135-21
Abstract: The SARS-CoV-2 pandemic has emphasized the need to understand the mechanisms of severe lung inflammatory pathology caused by human deadly coronaviruses in order to design new antiviral therapies. Here, we identify miRNA-223-3p as a host… read more here.
Keywords: mirna 223; sars cov; lung inflammatory; infection ... See more keywords
The Value of MicroRNAs as an Indicator of the Severity and the Acute Phase of Spinal Cord Injury
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DOI: 10.5535/arm.2019.43.3.328
Abstract: Objective To assess the role of miRNA-21 and miRNA-223 in a balloon-compression model of spinal cord injury (SCI). Methods A total of 50 male Wistar rats (n=50) were divided into the three groups: the group… read more here.
Keywords: mirna 223; three groups; expression; expression levels ... See more keywords
miRNA-223 Suppresses Mouse Gallstone Formation by Targeting Key Transporters in Hepatobiliary Cholesterol Secretion Pathway
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DOI: 10.7150/ijbs.65485
Abstract: miRNA-223 has been previously reported to play an essential role in hepatic cholesterol homeostasis. However, its role in regulation of biliary cholesterol secretion and gallstone formation remains unknown. Hence, mice with conventional knockout (KO), hepatocyte-specific… read more here.
Keywords: cholesterol secretion; mirna 223; cholesterol; gallstone formation ... See more keywords