Practical Procedures for Improving Detection of Circulating miRNAs in Cardiovascular Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-020-10019-2
Abstract: Hemolysis has been known to affect the measurement of circulating biomarkers. In this study, clinically applicable procedures for microRNA (miRNA) detection in serum samples of acute myocardial infarction patients were established. The 89 samples from… read more here.
Keywords: detection; practical procedures; hemolysis; procedures improving ... See more keywords
Luminescent quantum dots for miRNA detection.
Sign Up to like & getrecommendations! Published in 2018 at "Talanta"
DOI: 10.1016/j.talanta.2017.11.011
Abstract: MicroRNAs (miRNAs) are a class of small non-coding RNAs that are involved in nearly all developmental processes and human pathologies. MiRNAs are considered to be promising biomarkers, since their dysregulation correlates with the development and… read more here.
Keywords: detection; luminescent quantum; dots mirna; mirna detection ... See more keywords
Nanoarchitecture Frameworks for Electrochemical miRNA Detection.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2018.11.012
Abstract: With revolutionary advances in next-generation sequencing, the human transcriptome has been comprehensively interrogated. These discoveries have highlighted the emerging functional and regulatory roles of a large fraction of RNAs suggesting the potential they might hold… read more here.
Keywords: detection; frameworks electrochemical; biology; electrochemical mirna ... See more keywords
Isothermal Amplification for MicroRNA Detection: From the Test Tube to the Cell.
Sign Up to like & getrecommendations! Published in 2017 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.7b00040
Abstract: MicroRNAs (miRNAs) are a class of small noncoding RNAs that act as pivotal post-transcriptional regulators of gene expression, thus involving in many fundamental cellular processes such as cell proliferation, migration, and canceration. The detection of… read more here.
Keywords: detection; isothermal amplification; test tube; cell ... See more keywords
A novel method for miRNA detection based on target-triggered transcription of a light-up RNA aptamer.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc07095a
Abstract: We herein describe a novel method for miRNA detection based on target-triggered transcription of a light-up RNA aptamer (TTRApt), consequently producing a highly enhanced fluorescence signal through specific binding of a light-up RNA aptamer to… read more here.
Keywords: light rna; rna aptamer; mirna detection; novel method ... See more keywords
Colorimetric miRNA detection based on self-primer-initiated CRISPR-Cas12a-assisted amplification.
Sign Up to like & getrecommendations! Published in 2023 at "BioTechniques"
DOI: 10.2144/btn-2023-0008
Abstract: miRNAs alter significantly throughout pregnancy to support the development of the fetus. However, sensitive detection of miRNA remains a challenge. Herein, a reliable miRNA detection approach integrating self-assembly-triggered signal amplification and CRISPR-Cas12a-system cleavage-based color generation is described.… read more here.
Keywords: amplification; crispr cas12a; detection; mirna detection ... See more keywords
A Combinational Approach for More Efficient miRNA Biosensing
Sign Up to like & getrecommendations! Published in 2022 at "Current Genomics"
DOI: 10.2174/1389202923666220204160912
Abstract: MicroRNAs, short single-stranded noncoding RNAs ranging in length from 18 ~ 24 bp, are found in all kingdoms of eukaryotes and even viruses. It was found that miRNAs are involved in a variety of biological… read more here.
Keywords: mirna biosensing; efficient mirna; mirna detection; based mirna ... See more keywords