NASMDR: a framework for miRNA-drug resistance prediction using efficient neural architecture search and graph isomorphism networks
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac338
Abstract: As a frontier field of individualized therapy, microRNA (miRNA) pharmacogenomics facilitates the understanding of different individual responses to certain drugs and provides a reasonable reference for clinical treatment. However, the known drug resistance-associated miRNAs are… read more here.
Keywords: efficient neural; graph; mirna drug; drug ... See more keywords
miRNA as Drug: Antagomir and Beyond.
Sign Up to like & getrecommendations! Published in 2023 at "Current pharmaceutical design"
DOI: 10.2174/1381612829666230220123150
Abstract: read more here.
Keywords: mirna drug; antagomir beyond; drug antagomir;
MiRNA-Drug Resistance Association Prediction Through the Attentive Multimodal Graph Convolutional Network
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.799108
Abstract: MiRNAs can regulate genes encoding specific proteins which are related to the efficacy of drugs, and predicting miRNA-drug resistance associations is of great importance. In this work, we propose an attentive multimodal graph convolution network… read more here.
Keywords: drug resistance; network; graph; mirna drug ... See more keywords