Predicting miRNA-disease associations based on lncRNA-miRNA interactions and graph convolution networks
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac495
Abstract: Increasing studies have proved that microRNAs (miRNAs) are critical biomarkers in the development of human complex diseases. Identifying disease-related miRNAs is beneficial to disease prevention, diagnosis and remedy. Based on the assumption that similar miRNAs… read more here.
Keywords: mirna interactions; disease; disease associations; lncrna mirna ... See more keywords
ISLMI:Predicting lncRNA-miRNA Interactions Based on Information Injection and Second-Order Graph Convolution Network.
Sign Up to like & getrecommendations! Published in 2022 at "IEEE/ACM transactions on computational biology and bioinformatics"
DOI: 10.1109/tcbb.2022.3215151
Abstract: Studies have shown that IncRNA-miRNA interactions can affect cellular expression at the level of gene molecules through a variety of regulatory mechanisms and have important effects on the biological activities of living organisms. Several biomolecular… read more here.
Keywords: information; network; mirna interactions; lncrna mirna ... See more keywords
miRbiom: Machine-learning on Bayesian causal nets of RBP-miRNA interactions successfully predicts miRNA profiles
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0258550
Abstract: Formation of mature miRNAs and their expression is a highly controlled process. It is very much dependent upon the post-transcriptional regulatory events. Recent findings suggest that several RNA binding proteins beyond Drosha/Dicer are involved in… read more here.
Keywords: seq; machine learning; mirna profiles; rbp mirna ... See more keywords
SPCMLMI: A structural perturbation-based matrix completion method to predict lncRNA–miRNA interactions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1032428
Abstract: Accumulating evidence indicated that the interaction between lncRNA and miRNA is crucial for gene regulation, which can regulate gene transcription, further affecting the occurrence and development of many complex diseases. Accurate identification of interactions between… read more here.
Keywords: matrix completion; structural perturbation; similarity; mirna interactions ... See more keywords
Identification of neoplasm-specific signatures of miRNA interactions by employing a systems biology approach
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DOI: 10.7717/peerj.14149
Abstract: MicroRNAs represent major regulatory components of the disease epigenome and they constitute powerful biomarkers for the accurate diagnosis and prognosis of various diseases, including cancers. The advent of high-throughput technologies facilitated the generation of a… read more here.
Keywords: mirna interactions; neoplasm specific; identification neoplasm; biology ... See more keywords