Construction of a disease‐specific lncRNA‐miRNA‐mRNA regulatory network reveals potential regulatory axes and prognostic biomarkers for hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3526
Abstract: Hepatocellular carcinoma (HCC) is a heterogeneous malignancy with a high incidence and poor prognosis. Exploration of the underlying mechanisms and effective prognostic indicators is conducive to clinical management and optimization of treatment. The RNA‐seq and… read more here.
Keywords: hcc; network; regulatory axes; lncrna mirna ... See more keywords
Integrated mRNA‐Seq and miRNA‐Seq analysis of PLCγ2‐overexpressing hepatocarcinoma cells and identification of the associated miRNA‐mRNA network
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29294
Abstract: Our previous study has discovered the positive effect of phospholipase Cγ 2 (PLCγ2) on the growth of hepatocarcinoma cells; however, the underlying mechanism is far from being understood. For this reason, this study attempts to… read more here.
Keywords: seq; mirna; hepatocarcinoma cells; mirna mrna ... See more keywords
Application of lncRNA–miRNA–mRNA ceRNA network analysis in the treatment of androgenic alopecia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24791
Abstract: Long noncoding RNAs (lncRNAs) can be used as competitive endogenous RNAs (ceRNAs) to bind to microRNAs (miRNAs) to regulate gene expression. Previous studies have demonstrated that ceRNAs play an important role in the development of… read more here.
Keywords: androgenic alopecia; mirna mrna; cerna network; lncrna mirna ... See more keywords
Methods for Predicting CircRNA-miRNA-mRNA Regulatory Networks: GreenCircRNA and PlantCircNet Databases as Study Cases.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1645-1_11
Abstract: Circular RNAs are molecules formed by 3'-5' ligation in a splicing reaction, the so-called backsplicing. Well described in other groups, especially in humans, circRNA studies that include prediction and validation in plants are recent. It… read more here.
Keywords: predicting circrna; methods predicting; circrna mirna; regulatory networks ... See more keywords
The Limitations of Existing Approaches in Improving MicroRNA Target Prediction Accuracy.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7046-9_10
Abstract: MicroRNAs (miRNAs) are small (18-24 nt) endogenous RNAs found across diverse phyla involved in posttranscriptional regulation, primarily downregulation of mRNAs. Experimentally determining miRNA-mRNA interactions can be expensive and time-consuming, making the accurate computational prediction of… read more here.
Keywords: mirna mrna; target; prediction accuracy; limitations existing ... See more keywords
The regulatory role of microRNA-mRNA co-expression in hepatitis B virus-associated acute liver failure.
Sign Up to like & getrecommendations! Published in 2019 at "Annals of hepatology"
DOI: 10.1016/j.aohep.2019.07.007
Abstract: INTRODUCTION AND OBJECTIVES Acute liver failure (ALF) is a dramatic disorder requiring intensive care. MicroRNAs (miRNAs) have been identified to play important roles in ALF. This study was performed to identify miRNA-mRNA co-expression network after… read more here.
Keywords: expression; acute liver; hepatitis virus; mrna expression ... See more keywords
The early response expression profiles of miRNA-mRNA in farmed yellow catfish (Pelteobagrus fulvidraco) challenged with Edwardsiella tarda infection.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104018
Abstract: Edwardsiella tarda, the bacterial pathogen that causes ascites disease and red-head disease, poses a serious threat to yellow catfish (Pelteobagrus fulvidraco) aquaculture. In this study, the spleens of E. tarda-infected and non-infected yellow catfish were… read more here.
Keywords: edwardsiella tarda; mir; catfish pelteobagrus; yellow catfish ... See more keywords
Identification of key genes and construction of CircRNA–miRNA–mRNA regulatory networks in osteoarthritis
Sign Up to like & getrecommendations! Published in 2019 at "Electronic Journal of Biotechnology"
DOI: 10.1016/j.ejbt.2018.11.004
Abstract: Background: Osteoarthritis (OA) is one of the most frequent degenerative joint diseases with high rate of disability, but its mode of action remains largely unclear. The current study was aimed at identifying key genes and… read more here.
Keywords: circrna mirna; regulatory networks; mrna regulatory; signaling pathway ... See more keywords
SU2 CORRELATION ANALYSIS OF miRNA AND mRNA EXPRESSION PROFILES IN PERIPHERAL BLOOD MONONUCLEAR CELLS FROM ADHD PATIENTS AND CONTROLS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.191
Abstract: Background Attention Deficit Hyperactivity Disorders (ADHD) is a neurodevelopmental disorder characterized by impairment in sustaining attention and inability to control impulses and modulate activity level. The aetiology of ADHD is complex, involving genetic and environmental… read more here.
Keywords: analysis; expression; mrna expression; mirna mrna ... See more keywords
Profiling of Mirna and Mrna in Eutopic and Ectopic Endometrial Tissues in Patients with Endometrioma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Minimally Invasive Gynecology"
DOI: 10.1016/j.jmig.2019.09.681
Abstract: Study Objective Profiling of miRNA and mRNA in eutopic and ectopic endometrial tissues in patients with endometrioma. Design A prospective cohort study. Setting This study was conducted at the Department of Operative Gynecology of V.I.… read more here.
Keywords: profiling mirna; mrna eutopic; eutopic ectopic; ectopic endometrial ... See more keywords
Integrated miRNA and mRNA expression analysis uncovers drug targets in laryngeal squamous cell carcinoma patients.
Sign Up to like & getrecommendations! Published in 2019 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2019.04.018
Abstract: OBJECTIVES The current treatment of laryngeal squamous cell carcinoma (LSCC) is based on radical surgery and radiotherapy resulting in high morbidity. Chemoradiotherapy has been used as alternative to organ sparing; however, several advanced cases presented… read more here.
Keywords: expression; laryngeal squamous; drug; mir ... See more keywords