Articles with "mirna p53" as a keyword



Huashi Jiedu Decoction Enhances 5-Fluorouracil Efficacy in Gastric Cancer via miRNA-21-3p/p53 Pathway

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Published in 2025 at "Drug Design, Development and Therapy"

DOI: 10.2147/dddt.s513371

Abstract: Purpose To explore the mechanism of Huashi Jiedu Decoction (HJD) synergizing with 5-fluorouracil (5-Fu) in gastric cancer (GC) therapy. Methods MicroRNAs (miRNAs) and genes involved in HJD-mediated GC treatment were identified using ultra-high-performance liquid chromatography… read more here.

Keywords: p53 pathway; jiedu decoction; mirna p53; gastric cancer ... See more keywords