Faecal miRNA profiles associated with age, sex, BMI, and lifestyle habits in healthy individuals
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-00014-1
Abstract: For their stability and detectability faecal microRNAs represent promising molecules with potential clinical interest as non-invasive diagnostic and prognostic biomarkers. However, there is no evidence on how stool miRNA profiles change according to an individual’s… read more here.
Keywords: age sex; mirna profiles; lifestyle habits; mirna ... See more keywords
A fecal miRNA signature by small RNA sequencing accurately distinguishes colorectal cancers: results from a multicentric study.
Sign Up to like & getrecommendations! Published in 2023 at "Gastroenterology"
DOI: 10.1053/j.gastro.2023.05.037
Abstract: BACKGROUND & AIMS Fecal tests currently used for colorectal cancer (CRC) screening show limited accuracy in detecting early tumors or precancerous lesions. In this respect, we comprehensively evaluated stool microRNA (miRNA) profiles as biomarkers for… read more here.
Keywords: signature; crc; mirna signature; mirna profiles ... See more keywords
Peripheral blood mononuclear cells‐expressed miRNA profiles derived from children with metabolic‐associated fatty liver disease and insulin resistance
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Obesity"
DOI: 10.1111/ijpo.12966
Abstract: miRNA have been proposed as potential biomarkers of metabolic diseases. read more here.
Keywords: cells expressed; mononuclear cells; blood mononuclear; peripheral blood ... See more keywords
miRbiom: Machine-learning on Bayesian causal nets of RBP-miRNA interactions successfully predicts miRNA profiles
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0258550
Abstract: Formation of mature miRNAs and their expression is a highly controlled process. It is very much dependent upon the post-transcriptional regulatory events. Recent findings suggest that several RNA binding proteins beyond Drosha/Dicer are involved in… read more here.
Keywords: seq; machine learning; mirna profiles; rbp mirna ... See more keywords
miRNA profiles change during grass pollen immunotherapy irrespective of clinical outcome.
Sign Up to like & getrecommendations! Published in 2022 at "Immunotherapy"
DOI: 10.2217/imt-2021-0217
Abstract: Background: Subcutaneous immunotherapy (SCIT) is widely used in the treatment of allergic rhinitis (AR). This study aimed to determine the expression of 48 miRNAs in patients with AR undergoing grass pollen SCIT and investigate relations… read more here.
Keywords: immunotherapy; profiles change; mirna profiles; grass pollen ... See more keywords
Comparison of plasma- and saliva-derived exosomal miRNA profiles reveals diagnostic potential in head and neck cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.971596
Abstract: Background: Head and neck squamous cell carcinomas (HNSCC) lack tumor-specific biomarkers. Exosomes from HNSCC patients carry immunomodulatory molecules, and correlate with clinical parameters. We compared miRNA profiles of plasma- and saliva-derived exosomes to reveal liquid… read more here.
Keywords: plasma saliva; mirna profiles; saliva derived; cancer ... See more keywords
Viral miRNAs Alter Host Cell miRNA Profiles and Modulate Innate Immune Responses
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00433
Abstract: Prevalence of the members of herpesvirus family in oral inflammatory diseases is increasingly acknowledged suggesting their likely role as an etiological factor. However, the underlying mechanisms remain obscure. In our recent miRNA profiling of healthy… read more here.
Keywords: mirna profiles; mirna; mir; immune responses ... See more keywords
Comparative Analysis of Serum microRNA in Diagnosed Ocular Sarcoidosis versus Idiopathic Uveitis with Ocular Manifestations of Sarcoidosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810749
Abstract: “Idiopathic” is the most common category of uveitis, representing cases in which a specific diagnosis has not been established despite work-up. Sarcoidosis is a systemic granulomatous disorder affecting multiple organs including the lungs, skin, kidneys,… read more here.
Keywords: sarcoidosis; ocular sarcoidosis; analysis; mirna profiles ... See more keywords