A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs
Sign Up to like & getrecommendations! Published in 2019 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2018.12.002
Abstract: Summary Tumor-initiating cells (TICs) contribute to drug resistance and tumor recurrence in cancers, thus experimental approaches to dissect the complexity of TICs are required to design successful TIC therapeutic strategies. Here, we show that miRNA-3′… read more here.
Keywords: dissect complexity; tumor initiating; mirna targeting; identify mirna ... See more keywords
Biochemical prediction of miRNA targeting
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.366.6472.1467-j
Abstract: Molecular Biology MicroRNAs (miRNAs) regulate most human messenger RNAs and play essential roles in diverse developmental and physiological processes. Correctly predicting the function of each miRNA requires a better understanding of miRNA targeting efficacy. McGeary… read more here.
Keywords: biochemical prediction; mirna; mirna targeting; prediction mirna ... See more keywords
Therapeutic Approaches Targeting miRNA in Systemic Lupus Erythematosus.
Sign Up to like & getrecommendations! Published in 2022 at "Acta medica Okayama"
DOI: 10.18926/amo/63887
Abstract: Systemic lupus erythematosus (SLE) is a potentially fatal systemic autoimmune disease, and its etiology involves both genetic and environmental factors such as sex hormone imbalance, genetic predisposition, epigenetic regulation, and immunological factors. Dysregulation of microRNA… read more here.
Keywords: lupus erythematosus; targeting therapy; systemic lupus; mirna targeting ... See more keywords