A review study on the modulation of SIRT1 expression by miRNAs in aging and age-associated diseases.
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DOI: 10.1016/j.ijbiomac.2021.08.013
Abstract: Sirtuin-1 (SIRT1) as a NAD + -dependent Class III protein deacetylase, involves in longevity and various cellular physiological processes. SIRT1 via deacetylating transcription factors regulates cell growth, inflammation, metabolism, hypoxic responses, cell survival, senescence, and aging. MicroRNAs… read more here.
Keywords: sirt1; associated diseases; expression; age associated ... See more keywords