β-TrCP-Mediated Proteolysis of Mis18β Prevents Mislocalization of CENP-A and Chromosomal Instability
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DOI: 10.1080/10985549.2024.2382445
Abstract: Abstract Restricting the localization of evolutionarily conserved histone H3 variant CENP-A to the centromere is essential to prevent chromosomal instability (CIN), an important hallmark of cancers. Overexpressed CENP-A mislocalizes to non-centromeric regions and contributes to… read more here.
Keywords: cenp; mislocalization cenp; trcp mediated; mis18 ... See more keywords