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Imaging Protein Misfolding in the Brain Using β-Sheet Ligands

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Published in 2018 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2018.00585

Abstract: Neurodegenerative diseases characterized by pathological protein accumulation in cells are termed “proteinopathies.” Although various protein aggregates share cross-β-sheet structures, actual conformations vary among each type of protein deposit. Recent progress in the development of radiotracers… read more here.

Keywords: protein; protein misfolding; imaging protein; pet tracers ... See more keywords