Misinterpretation risks of global stochastic optimisation of kinetic models revealed by multiple optimisation runs.
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DOI: 10.1016/j.mbs.2018.11.002
Abstract: One of use cases for metabolic network optimisation of biotechnologically applied microorganisms is the in silico design of new strains with an improved distribution of metabolic fluxes. Global stochastic optimisation methods (genetic algorithms, evolutionary programing,… read more here.
Keywords: misinterpretation; biology; misinterpretation risks; optimisation ... See more keywords