Recognition and Degradation of Mislocalized Proteins in Health and Disease.
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DOI: 10.1101/cshperspect.a033902
Abstract: A defining feature of eukaryotic cells is the segregation of complex biochemical processes among different intracellular compartments. The protein targeting, translocation, and trafficking pathways that sustain compartmentalization must recognize a diverse range of clients via… read more here.
Keywords: degradation; proteins health; recognition degradation; disease ... See more keywords
A Novel Approach to Relocate Misplaced Proteins in Cells
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DOI: 10.3390/biology14040420
Abstract: Simple Summary Humans are composed of millions of proteins that help regulate important cellular processes. However, these proteins must be in the correct location to function properly. Proteins that become mislocalized can accumulate and cause… read more here.
Keywords: mislocalized proteins; novel approach; approach relocate; misplaced proteins ... See more keywords