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Published in 2022 at "European Radiology"
DOI: 10.1007/s00330-022-08607-8
Abstract: To reveal a radiogenomic correlation between the presence of the T2-fluid-attenuated inversion recovery resection (T2-FLAIR) mismatch sign on MR images and isocitrate dehydrogenase (IDH) mutation status in adult patients with lower-grade gliomas (LGGs). A web-based…
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Keywords:
mismatch sign;
sign;
flair mismatch;
idh mutation ... See more keywords
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Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa041
Abstract: The T2-FLAIR mismatch sign is an easily detectable imaging sign on routine clinical MRI studies that suggests diagnosis of IDH-mutant 1p/19q non-codeleted gliomas. Multiple independent studies show that the T2-FLAIR mismatch sign has near-perfect specificity,…
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Keywords:
flair mismatch;
idh mutant;
sign;
imaging sign ... See more keywords
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Published in 2023 at "Journal of veterinary internal medicine"
DOI: 10.1111/jvim.16749
Abstract: BACKGROUND In humans, the T2-weighted (T2W)-fluid-attenuated inversion recovery (FLAIR) mismatch sign (T2FMM) is a specific imaging biomarker for the isocitrate dehydrogenase 1 (IDH1)-mutated, 1p/19q non-codeleted low-grade astrocytomas (LGA). The T2FMM is characterized by a homogeneous…
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Keywords:
flair mismatch;
biomarker;
t2fmm;
mismatch sign ... See more keywords
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Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-17-0560
Abstract: Purpose: Lower-grade gliomas (WHO grade II/III) have been classified into clinically relevant molecular subtypes based on IDH and 1p/19q mutation status. The purpose was to investigate whether T2/FLAIR MRI features could distinguish between lower-grade glioma…
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Keywords:
flair mismatch;
mismatch sign;
lower grade;
flair ... See more keywords
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Published in 2023 at "Cancers"
DOI: 10.3390/cancers15092503
Abstract: Simple Summary The preoperative risk estimation of non-enhancing suspected “low-grade” glioma (NEG) is key in determining the optimal timing of diagnosis and treatment to delay malignant progression and avoid undertreatment. The updated 2021 WHO classification…
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Keywords:
flair mismatch;
non enhancing;
mismatch sign;
risk estimation ... See more keywords