Radiogenomic association between the T2-FLAIR mismatch sign and IDH mutation status in adult patients with lower-grade gliomas: an updated systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Radiology"
DOI: 10.1007/s00330-022-08607-8
Abstract: To reveal a radiogenomic correlation between the presence of the T2-fluid-attenuated inversion recovery resection (T2-FLAIR) mismatch sign on MR images and isocitrate dehydrogenase (IDH) mutation status in adult patients with lower-grade gliomas (LGGs). A web-based… read more here.
Keywords: mismatch sign; sign; flair mismatch; idh mutation ... See more keywords
'Real world' use of a highly reliable imaging sign: 'T2-FLAIR mismatch' for identification of IDH mutant astrocytomas.
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa041
Abstract: The T2-FLAIR mismatch sign is an easily detectable imaging sign on routine clinical MRI studies that suggests diagnosis of IDH-mutant 1p/19q non-codeleted gliomas. Multiple independent studies show that the T2-FLAIR mismatch sign has near-perfect specificity,… read more here.
Keywords: flair mismatch; idh mutant; sign; imaging sign ... See more keywords
P03.13.B CORTICAL DWI-GD MISMATCH SIGN AS A SPECIFIC IMAGING BIOMARKER OF PRIMARY CNS LYMPHOMA
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DOI: 10.1093/neuonc/noaf193.172
Abstract: Previous studies have focused on differentiating glioblastoma, IDH-wildtype (GB), from primary CNS lymphoma (PCNSL) based on the peritumoral area and white matter invasion. In this study, we will focus on the peritumoral area of the… read more here.
Keywords: sign; cortical dwi; dwi mismatch; mismatch sign ... See more keywords
The T2-FLAIR mismatch sign as an imaging biomarker for oligodendrogliomas in dogs.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of veterinary internal medicine"
DOI: 10.1111/jvim.16749
Abstract: BACKGROUND In humans, the T2-weighted (T2W)-fluid-attenuated inversion recovery (FLAIR) mismatch sign (T2FMM) is a specific imaging biomarker for the isocitrate dehydrogenase 1 (IDH1)-mutated, 1p/19q non-codeleted low-grade astrocytomas (LGA). The T2FMM is characterized by a homogeneous… read more here.
Keywords: flair mismatch; biomarker; t2fmm; mismatch sign ... See more keywords
T2–FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower-grade Gliomas: A TCGA/TCIA Project
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-17-0560
Abstract: Purpose: Lower-grade gliomas (WHO grade II/III) have been classified into clinically relevant molecular subtypes based on IDH and 1p/19q mutation status. The purpose was to investigate whether T2/FLAIR MRI features could distinguish between lower-grade glioma… read more here.
Keywords: flair mismatch; mismatch sign; lower grade; flair ... See more keywords
Adoption of the T2-FLAIR Mismatch Sign among Radiologists: How Well Are We Doing?
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Neuroradiology"
DOI: 10.3174/ajnr.a8783
Abstract: BACKGROUND AND PURPOSE: The classic T2-FLAIR mismatch sign is a highly specific MRI feature that can aid in preoperative diagnosis of isocitrate dehydrogenase (IDH)-mutant 1p/19q noncodeleted gliomas and affect surgical planning. This study aimed to… read more here.
Keywords: idh mutant; flair mismatch; mismatch sign;
Risk Estimation in Non-Enhancing Glioma: Introducing a Clinical Score
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DOI: 10.3390/cancers15092503
Abstract: Simple Summary The preoperative risk estimation of non-enhancing suspected “low-grade” glioma (NEG) is key in determining the optimal timing of diagnosis and treatment to delay malignant progression and avoid undertreatment. The updated 2021 WHO classification… read more here.
Keywords: flair mismatch; non enhancing; mismatch sign; risk estimation ... See more keywords