Parkin promotes proteasomal degradation of misregulated BAX
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DOI: 10.1242/jcs.200162
Abstract: ABSTRACT The pro-apoptotic BCL-2 protein BAX commits human cells to apoptosis by permeabilizing the outer mitochondrial membrane. BAX activation has been suggested to require the separation of helix α5 from α6 – the ‘latch’ from… read more here.
Keywords: bax; misregulated bax; pro apoptotic; retrotranslocation ... See more keywords