The Patients’ Perspective Is the Missing Link in Current Bariatric Surgical Practice
Sign Up to like & getrecommendations! Published in 2017 at "Obesity Surgery"
DOI: 10.1007/s11695-017-2787-2
Abstract: Dear editor, Bariatric surgery is changing. Nowadays, the obesity epidemic has reached enormous proportions, even in developing countries [1]. Secondly, the presence of concomitant disease and also comorbidities makes the treatment even more challenging. Based… read more here.
Keywords: treatment; group; link current; missing link ... See more keywords
Are Tanycytes the Missing Link Between Type 2 Diabetes and Alzheimer’s Disease?
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1123-8
Abstract: Tanycytes are highly specialized bipolar ependymal cells that line the ventrolateral wall and the floor of the third ventricle in the brain and form a blood-cerebrospinal fluid barrier at the level of the median eminence.… read more here.
Keywords: alzheimer disease; type diabetes; missing link; type ... See more keywords
Inflammation in Mental Disorders: Is the Microbiota the Missing Link?
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-020-00535-1
Abstract: Research suggests that inflammation is important in the pathophysiology of mental disorders. In addition, a growing body of evidence has led to the concept of the microbiota-gut-brain axis. To understand the potential interactions, we begin… read more here.
Keywords: microbiota missing; inflammation mental; inflammation; missing link ... See more keywords
JPT2: The missing link between intracellular Ca2+ release channels and NAADP?
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102405
Abstract: NAADP (nicotinic acid adenine dinucleotide phosphate) is a potent second messenger releasing Ca2+ from endolysosomes through two-pore channels (TPCs) and from the endoplasmic reticulum (ER) through type 1 ryanodine receptors (RyR1). How NAADP activates these… read more here.
Keywords: link intracellular; link; ca2 release; jpt2 missing ... See more keywords
HIV-1-Associated Atherosclerosis: Unraveling the Missing Link.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.05.012
Abstract: Cardiovascular disease, including atherosclerosis and atherosclerosis-associated complications, is an increasing cause of morbidity and mortality in human immunodeficiency virus (HIV) patients in the post-antiretroviral therapy era. HIV alone accelerates atherosclerosis. Antiretroviral therapy; HIV-associated comorbidities, such… read more here.
Keywords: associated atherosclerosis; hiv; missing link; hiv associated ... See more keywords
Intrauterine Microbiota: Missing, or the Missing Link?
Sign Up to like & getrecommendations! Published in 2019 at "Trends in Neurosciences"
DOI: 10.1016/j.tins.2019.03.008
Abstract: The intrauterine environment provides a key interface between the mother and the developing fetus during pregnancy, and is a target for investigating mechanisms of fetal programming. Studies have demonstrated an association between prenatal stress and… read more here.
Keywords: microbiota missing; intrauterine microbiota; missing missing; missing link ... See more keywords
The Missing Link between (Un)druggable and Degradable KRAS
Sign Up to like & getrecommendations! Published in 2020 at "ACS Central Science"
DOI: 10.1021/acscentsci.0c00920
Abstract: Design, synthesis, and biological evaluation of the first cell active KRASG12C chimeric degrader. read more here.
Keywords: degradable kras; missing link; druggable degradable; link druggable ... See more keywords
Calix[3]pyrrole: A Missing Link in Porphyrin-Related Chemistry.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c06331
Abstract: A long-standing question in porphyrin chemistry is why pyrrole monomers selectively form tetrapyrrolic macrocycles, whereas the corresponding tripyrrolic macrocycles are never observed. Calix[3]pyrrole, a tripyrrolic porphyrinogen-like macrocycle bearing three sp3-carbon linkages, is a missing link… read more here.
Keywords: calix pyrrole; missing link; chemistry;
Missing Link in the Growth of Lead-Based Zintl Clusters: Isolation of the Dimeric Plumbaspherene [Cu4Pb22]4.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c10106
Abstract: We report here the structure of an endohedral plumbaspherene, [Cu4Pb22]4-, the gold analogue of which was previously postulated to be a "missing link" in the growth of larger clusters containing three and four icosahedral subunits.… read more here.
Keywords: growth; link growth; plumbaspherene cu4pb22; missing link ... See more keywords
TEtraQuinolines: A Missing Link in the Family of Porphyrinoid Macrocycles.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c12582
Abstract: Porphyrin contains four inwardly oriented nitrogen atoms. It is arguably the most ubiquitous multifunctional naturally occurring macrocycle that has inspired the design of novel nitrogen-containing heterocycles for decades. While cyclic tetramers of pyrrole, indole, and… read more here.
Keywords: family porphyrinoid; family; tetraquinolines missing; link family ... See more keywords
The missing link: allostery and catalysis in the anti-viral protein SAMHD1
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Society Transactions"
DOI: 10.1042/bst20180348
Abstract: Vertebrate protein SAMHD1 (sterile-α-motif and HD domain containing protein 1) regulates the cellular dNTP (2′-deoxynucleoside-5′-triphosphate) pool by catalysing the hydrolysis of dNTP into 2′-deoxynucleoside and triphosphate products. As an important regulator of cell proliferation and… read more here.
Keywords: link allostery; samhd1; protein samhd1; missing link ... See more keywords