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   Articles with "misuse potential" as a keyword



NLX-112, a highly selective 5-HT1A receptor biased agonist, does not exhibit misuse potential in male rats or macaques

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recommendations! Published in 2022 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2022.109025

Abstract: NLX-112 (a.k.a. F13640 or befiradol) exhibits nanomolar affinity, exceptional selectivity and biased agonism at serotonin 5-HT1A receptors. NLX-112 displays robust analgesic activity in a number of rodent models of pain, and is currently developed as… read more here.

Keywords: misuse potential; ht1a; nlx 112; icss ... See more keywords

Monitoring of drug misuse or potential misuse in a nationwide healthcare insurance database: A cross-sectional study in France.

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recommendations! Published in 2018 at "Therapie"

DOI: 10.1016/j.therap.2018.12.007

Abstract: AIM OF THE STUDY To provide a tool for drug misuse or potential misuse monitoring by using a healthcare insurance database. METHODS A cross-sectional study repeated quarterly from 2007 to 2014 was conducted using data… read more here.

Keywords: misuse; study; drug; drug misuse ... See more keywords

Clinical Presentations of Bupropion Prescription Drug Misuse

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recommendations! Published in 2024 at "Journal of Clinical Psychopharmacology"

DOI: 10.1097/jcp.0000000000001858

Abstract: Abstract Background Among prescribers, bupropion is considered a substance of low misuse potential, with some studies showing lesser misuse potential than caffeine. However, several case reports exist of recreational bupropion misuse and diversion. Our goal… read more here.

Keywords: history; disorder; misuse potential; use ... See more keywords
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Addressing the Misuse Potential of Life Science Research—Perspectives From a Bottom-Up Initiative in Switzerland

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recommendations! Published in 2018 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2018.00038

Abstract: Codes of conduct have received wide attention as a bottom-up approach to foster responsibility for dual use aspects of life science research within the scientific community. In Switzerland, a series of discussion sessions led by… read more here.

Keywords: research; science research; life science; misuse potential ... See more keywords