MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST
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DOI: 10.1371/journal.ppat.1010989
Abstract: The mediator of IRF3 activation (MITA, also named STING) is critical for immune responses to abnormal cytosolic DNA and has been considered an important drug target in the clinical therapy of tumors and autoimmune diseases.… read more here.
Keywords: viral infection; mita oligomerization; glycosylation; ddost ... See more keywords