MITF-High and MITF-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
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DOI: 10.1158/1078-0432.ccr-17-0010
Abstract: Purpose: Understanding tumor heterogeneity is an important challenge in current cancer research. Transcription and epigenetic profiling of cultured melanoma cells have defined at least two distinct cell phenotypes characterized by distinctive gene expression signatures associated… read more here.
Keywords: mitf high; mitf; heterogeneity; gene expression ... See more keywords