Mitigating Matrix Effects in LC-ESI-MS/MS Analysis of a Urinary Biomarker of Xylenes Exposure.
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DOI: 10.1093/jat/bkac046
Abstract: Liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) with stable isotope labeled internal standards (SIL-IS) is the gold standard for quantitative analysis of drugs and metabolites in complex biological samples. Significant isotopic effects associated with deuterium labeling… read more here.
Keywords: xylenes exposure; mitigating matrix; 2mha 13c6; analysis ... See more keywords