Prevention of High-Level Daptomycin-Resistance Emergence In Vitro in Streptococcus mitis-oralis by Using Combination Antimicrobial Strategies
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DOI: 10.1007/s00284-018-1491-3
Abstract: Among the viridans group streptococci, S. mitis-oralis strains are frequently resistant to multiple β-lactams and tolerant to vancomycin (VAN). This scenario has led to the proposed clinical use of newer agents, like daptomycin (DAP) for such… read more here.
Keywords: emergence; high level; mitis oralis; dap ... See more keywords
Resolving Phylogenetic Relationships for Streptococcus mitis and Streptococcus oralis through Core- and Pan-Genome Analyses
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DOI: 10.1093/gbe/evz049
Abstract: Abstract Taxonomic and phylogenetic relationships of Streptococcus mitis and Streptococcus oralis have been difficult to establish biochemically and genetically. We used core-genome analyses of S. mitis and S. oralis, as well as the closely related… read more here.
Keywords: mitis oralis; streptococcus mitis; phylogenetic relationships; mitis ... See more keywords
Perturbations of Phosphatidate Cytidylyltransferase (CdsA) Mediate Daptomycin Resistance in Streptococcus mitis/oralis by a Novel Mechanism
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DOI: 10.1128/aac.02435-16
Abstract: ABSTRACT Streptococcus mitis/oralis is an important pathogen, causing life-threatening infections such as endocarditis and severe sepsis in immunocompromised patients. The β-lactam antibiotics are the usual therapy of choice for this organism, but their effectiveness is… read more here.
Keywords: mechanism; mitis oralis; streptococcus mitis; resistance ... See more keywords
Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis
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DOI: 10.1186/s12866-020-01849-w
Abstract: Viridans group streptococci of the Streptococcus mitis-oralis subgroup are important endovascular pathogens. They can rapidly develop high-level and durable non-susceptibility to daptomycin both in vitro and in vivo upon exposure to daptomycin. Two consistent genetic… read more here.
Keywords: daptomycin; daptomycin non; mitis oralis; non susceptible ... See more keywords
Identification of Emerging Human Mastitis Pathogens by MALDI-TOF and Assessment of Their Antibiotic Resistance Patterns
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DOI: 10.3389/fmicb.2017.01258
Abstract: Lactational mastitis constitutes one of the main causes of undesired weaning, depriving the mother–infant pair from the benefits of breastfeeding; therefore, this condition should be considered a relevant public health issue. The role of specific… read more here.
Keywords: mastitis; maldi tof; mitis oralis; resistance ... See more keywords