Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-01322-4
Abstract: Alveolar epithelial type II (AETII) cells are important for lung epithelium maintenance and function. We demonstrate that AETII cells from mouse lungs exposed to cigarette smoke (CS) increase the levels of the mitochondria-encoded non-coding RNA,… read more here.
Keywords: ncr 805; retrograde signaling; mito ncr; non coding ... See more keywords
A Synthetic Small RNA Homologous to the D-Loop Transcript of mtDNA Enhances Mitochondrial Bioenergetics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.772313
Abstract: Mitochondrial malfunction is a hallmark of many diseases, including neurodegenerative disorders, cardiovascular and lung diseases, and cancers. We previously found that alveolar progenitor cells, which are more resistant to cigarette smoke-induced injury than the other… read more here.
Keywords: mito ncr; ncr 805; mitochondrial bioenergetics; mtdna ... See more keywords