Effects of freezing extender supplementation with mitochondria-targeted antioxidant Mito-TEMPO on frozen-thawed rooster semen quality and reproductive performance.
Sign Up to like & getrecommendations! Published in 2020 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2020.106671
Abstract: Rooster semen cryopreservation is a useful method to utilize semen samples for artificial insemination in commercial flocks, but with use of the freezing-thawing process there is a reduction in the quality and fertilization capacity of… read more here.
Keywords: mitochondria targeted; rooster semen; mito; mito tempo ... See more keywords
Substrate binding in the multidrug transporter MdfA in detergent solution and in lipid nanodiscs.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.03.014
Abstract: MdfA from Escherichia coli is a prototypical secondary multi-drug (Mdr) transporter that exchanges drugs for protons. MdfA mediated drug efflux is driven by the proton gradient and enabled by conformational changes, which accompany the recruitment… read more here.
Keywords: deer; iii; lipid nanodiscs; mito tempo ... See more keywords
Flow cytometry study of post-thawed bulk spermatozoa: Mito-TEMPO improves cryopreservation performance by controlling apoptosis rate, DNA fragmentation and ROS production.
Sign Up to like & getrecommendations! Published in 2021 at "Cryobiology"
DOI: 10.1016/j.cryobiol.2021.09.008
Abstract: Sperm cryopreservation is used to spread qualified semen for artificial insemination, but the freezing process reduces sperm quality. This study assessed the efficacy of Mito-TEMPO on post-thawed goat sperm quality. Semen samples divided to five… read more here.
Keywords: mito tempo; post thawed; dna fragmentation;
Mito‐TEMPO, a mitochondria‐targeted antioxidant, prevents N‐nitrosodiethylamine‐induced hepatocarcinogenesis in mice
Sign Up to like & getrecommendations! Published in 2019 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2019.03.037
Abstract: Background: Oxidative stress and mitochondrial dysfunction play a significant role in hepatocarcinogenesis. Mitochondria are source organelle as well as target for free radicals. The oxidative damage to mitochondria can be prevented by mitochondria‐targeted antioxidant, mito‐TEMPO.… read more here.
Keywords: mitochondria targeted; mito tempo; hepatocarcinogenesis; targeted antioxidant ... See more keywords
Mito-TEMPO protects against bisphenol-A-induced testicular toxicity: an in vivo study
Sign Up to like & getrecommendations! Published in 2022 at "Free Radical Research"
DOI: 10.1080/10715762.2022.2133702
Abstract: Abstract Bisphenol-A (BPA) is a common environmental toxin which alters testicular function in both animals and humans. BPA exerts its cytotoxic potential by altering mitochondrial oxidative stress and functioning. Therefore, protecting mitochondria from oxidative stress… read more here.
Keywords: mitochondrial complex; tempo; oxidative stress; induced testicular ... See more keywords
Comparison of Candesartan and Angiotensin-(1-7) Combination to Mito-TEMPO Treatment for Normalizing Blood Pressure and Sympathovagal Balance in (mREN2)27 Rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000645
Abstract: Abstract: Hypertensive transgenic (mRen2)27 rats exhibit impaired baroreflex sensitivity (BRS) for control of heart rate (HR). Intracerebroventricular infusion of Ang-(1-7) improves indices of vagal BRS independent of lowering mean arterial pressure (MAP), whereas AT1 receptor… read more here.
Keywords: mren2 rats; mito tempo; treatment; balance ... See more keywords
Effect of mito-TEMPO, a mitochondria-targeted antioxidant, in rats with neuropathic pain
Sign Up to like & getrecommendations! Published in 2018 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001105
Abstract: The therapeutic effects of mitochondria-targeted antioxidants have been demonstrated in many pathological conditions, but their effect on neuropathic pain remains unclear. The objective was to study the therapeutic effects and mechanisms of mito-TEMPO (MT), as… read more here.
Keywords: mito tempo; mitochondria targeted; neuropathic pain; cci ... See more keywords
Supplementation of Mito TEMPO and Acetovanillone in semen extender improves freezability of buffalo spermatozoa.
Sign Up to like & getrecommendations! Published in 2022 at "Andrology"
DOI: 10.1111/andr.13158
Abstract: BACKGROUND Oxidative stress is one of the leading factors responsible for poor post-thaw semen quality due to overproduction of reactive oxygen species (ROS) over neutralizing antioxidants present in semen. Mainly two ROS generation sites are… read more here.
Keywords: mito tempo; tempo acetovanillone; acetovanillone; group ... See more keywords