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2
Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14567
Abstract: Previously, we showed that an aberrant accumulation of activated Ras in mitochondria correlates with an increase in apoptosis. In this article, we show that lack of trehalose‐6P‐synthase, known to trigger apoptosis in Saccharomyces cerevisiae, induces localization…
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Keywords:
active ras2;
pka pathway;
regulated cell;
mitochondria ... See more keywords
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1
Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201611
Abstract: Reversibly controlling the dye arrangements in living systems has great potential to realize spatiotemporally controlled photomedicine. However, tuning or even maintaining a certain arrangement of dyes in a complex living environments is extremely challenging due…
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Keywords:
controlled photomedicine;
driven dye;
dye rearrangement;
mitochondria ... See more keywords
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1
Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202200774
Abstract: The targeting of bioactive molecules and probes to mitochondria can be achieved by coupling to the lipophilic triphenyl phosphonium (TPP) cation, which accumulates several hundred‐fold within mitochondria in response to the mitochondrial membrane potential (Δψm).…
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Keywords:
mitochondria targeted;
linker;
enhance;
within mitochondria ... See more keywords
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Published in 2022 at "International Journal for Numerical Methods in Biomedical Engineering"
DOI: 10.1002/cnm.3648
Abstract: We report a computational study of mitochondria transport in a branched axon with two branches of different sizes. For comparison, we also investigate mitochondria transport in an axon with symmetric branches and in a straight…
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Keywords:
computational study;
mitochondria transport;
age;
mitochondria age ... See more keywords
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Published in 2017 at "Current Protocols in Cell Biology"
DOI: 10.1002/cpcb.26
Abstract: Subcellular fractionation techniques are essential for cell biology and drug development studies. The emergence of organelle‐targeted nanoparticle (NP) platforms necessitates the isolation of target organelles to study drug delivery and activity. Mitochondria‐targeted NPs have attracted…
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Keywords:
iron oxide;
mitochondria;
biology;
mitochondria using ... See more keywords
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Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22376
Abstract: Nickel oxide nanoparticles (NiO‐NPs) are progressively used for an immense number of new applications in modern industries sectors. Nevertheless, the toxic impact of NiO‐NPs has not been clearly elucidated on human melanoma cell lines at…
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Keywords:
melanoma;
nio nps;
oxide nanoparticles;
mitochondria ... See more keywords
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Published in 2018 at "Small"
DOI: 10.1002/smll.201703306
Abstract: Mitochondria-mediated apoptosis (MMA) is a preferential option for cancer therapy due to the presence of cell-suicide factors in mitochondria, however, low permeability of mitochondria is a bottleneck for targeting drug delivery. In this paper, glycyrrhetinic…
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Keywords:
graphene oxide;
glycyrrhetinic acid;
functionalized graphene;
delivery ... See more keywords
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1
Published in 2021 at "Small"
DOI: 10.1002/smll.202103086
Abstract: Mitochondrial dysfunction is considered to be an important factor that leads to aging and premature aging diseases. Transferring mitochondria to cells is an emerging and promising technique for the therapy of mitochondrial deoxyribonucleic acid (mtDNA)-related…
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Keywords:
optical tweezers;
automated optical;
mitochondria;
transfer ... See more keywords
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1262-0_10
Abstract: Research on mitochondria-targeted active molecules became a hot topic in the past decade. Development of mitochondria permeability transition pore (mPTP )-targeting agents with clinical applications is needed not only because of the importance of the…
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Keywords:
nature antioxidant;
gallic acid;
mitochondria;
bridging gap ... See more keywords
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1262-0_16
Abstract: Multifunctional nanoplatforms are promising scaffolds for biomedical applications such as bioimaging, chemical/biological sensors, drug delivery, and cancer diagnosis and/or treatments. Mitochondria play crucial roles in metabolism of eukaryotic cells; therefore, mitochondria-targeting molecule such as triphenylphosphonium…
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Keywords:
carbon quantum;
mitochondria;
fluorescent carbon;
quantum dots ... See more keywords
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1266-8_2
Abstract: As the powerhouse of the cell, mitochondria, plays a crucial role in many aspects of life, whereby mitochondrial dysfunctions are associated with pathogenesis of many diseases, like neurodegenerative diseases, obesity, cancer, and metabolic as well…
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Keywords:
preparation functional;
mitochondria;
challenging business;
functional mitochondria ... See more keywords