Articles with "mitochondria associated" as a keyword



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Effects of mitochondria‐associated Ca2+ transporters suppression on oocyte activation

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Published in 2020 at "Cell Biochemistry and Function"

DOI: 10.1002/cbf.3571

Abstract: Oocyte activation deficiency leads to female infertility. [Ca2+]i oscillations are required for mitochondrial energy supplement transition from the resting to the excited state, but the underlying mechanisms are still very little known. Three mitochondrial Ca2+… read more here.

Keywords: associated ca2; effects mitochondria; mitochondria associated; ca2 ... See more keywords
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Systematic In‐Depth Proteomic Analysis of Mitochondria‐Associated Endoplasmic Reticulum Membranes in Mouse and Human Testes

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Published in 2018 at "PROTEOMICS"

DOI: 10.1002/pmic.201700478

Abstract: Mitochondria‐associated endoplasmic reticulum membranes (MAMs) regulate important cellular functions including calcium signaling, bioenergetics, and apoptosis during neurodevelopment and carcinogenesis, but its function in male reproduction and spermatogenesis remains enigmatic because the field lacks a complete… read more here.

Keywords: endoplasmic reticulum; analysis; associated endoplasmic; mitochondria associated ... See more keywords
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Regulation of Mitochondrial Dynamics and Autophagy by the Mitochondria-Associated Membrane.

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Published in 2017 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-981-10-4567-7_3

Abstract: Mitochondria are powerhouses and central to metabolism in cells. They are highly dynamic organelles that continuously fuse, divide, and move along the cytoskeleton to form the mitochondrial network. The fusion and fission are catalyzed by… read more here.

Keywords: regulation mitochondrial; endoplasmic reticulum; mitochondria associated; associated membrane ... See more keywords
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Mitochondria-associated membranes (MAMs): An emerging platform connecting energy and immune sensing to metabolic flexibility.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.06.097

Abstract: Living organisms have the capacity to sense both nutrients and immune signals in order to adapt their metabolism to the needs, and both metabolic inflexibility and exacerbated immune responses are associated with metabolic diseases. Over… read more here.

Keywords: immune; metabolic diseases; mitochondria associated; associated membranes ... See more keywords
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Stasimon/Tmem41b localizes to mitochondria-associated ER membranes and is essential for mouse embryonic development.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.10.073

Abstract: Stasimon (also known as Tmem41b) is an evolutionarily conserved transmembrane protein first identified for its contribution to motor system dysfunction in animal models of the childhood neurodegenerative disease spinal muscular atrophy (SMA). Stasimon was shown… read more here.

Keywords: localizes mitochondria; embryonic development; mitochondria associated; associated membranes ... See more keywords
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Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes

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Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109134

Abstract: SUMMARY Axonal generation of Alzheimer’s disease (AD)-associated amyloid-β (Aβ) plays a key role in AD neuropathology, but the cellular mechanisms involved in its release have remained elusive. We previously reported that palmitoylated APP (palAPP) partitions… read more here.

Keywords: endoplasmic reticulum; axonal generation; associated endoplasmic; generation ... See more keywords
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The effects of mitochondria-associated long noncoding RNAs in cancer mitochondria: New players in an old arena.

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Published in 2018 at "Critical reviews in oncology/hematology"

DOI: 10.1016/j.critrevonc.2018.08.005

Abstract: LncRNAs, as new players in the old battle against cancer, are significant components of gene regulatory networks. Mitochondria-associated lncRNAs have newly been discovered to work in concert with transcription factors and epigenetic regulators to modulate… read more here.

Keywords: players old; associated lncrnas; mitochondria associated; cancer ... See more keywords
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PACS: 2: A Key Regulator of Mitochondria-Associated Membranes (MAMs).

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Published in 2020 at "Pharmacological research"

DOI: 10.1016/j.phrs.2020.105080

Abstract: Mitochondria-associated membranes (MAMs) are the organellar contact sites between mitochondria and the endoplasmic reticulum (ER), and recent studies demonstrated that MAMs, which serve as multiple scaffolds of proteins, are involved in Ca2+ signaling, lipid metabolism,… read more here.

Keywords: mitochondria associated; associated membranes; pacs key; membranes mams ... See more keywords
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Disruption of the mitochondria‐associated ER membrane (MAM) plays a central role in palmitic acid–induced insulin resistance

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Published in 2017 at "Experimental Cell Research"

DOI: 10.1016/j.yexcr.2017.08.006

Abstract: &NA; The mitochondria‐associated ER membrane (MAM) is a specialized subdomain of ER that physically connects with mitochondria. Although disruption of inter‐organellar crosstalk via the MAM impairs cellular homeostasis, its pathological significance in insulin resistance in… read more here.

Keywords: mam; mitochondria associated; acid; insulin resistance ... See more keywords
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Mitochondria‐associated endoplasmic reticulum membrane: Overview and inextricable link with cancer

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Published in 2023 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.17696

Abstract: The mitochondrial‐associated membrane (MAM) is a physical platform that facilitates communication between the endoplasmic reticulum (ER) and mitochondria. It is enriched with many proteins and enzymes and plays an important role in the regulation of… read more here.

Keywords: endoplasmic reticulum; membrane; cancer; associated endoplasmic ... See more keywords
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Mitochondria Associated MicroRNA Expression Profiling of Heart Failure

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Published in 2017 at "BioMed Research International"

DOI: 10.1155/2017/4042509

Abstract: Heart failure (HF) is associated with mitochondrial dysfunction and energy metabolism impairment. MicroRNAs are implicated in the development of heart failure. However, the mitochondria enriched microRNA during heart failure remains elusive. Here, we generated a… read more here.

Keywords: heart; heart failure; mitochondria associated; expression ... See more keywords