Characterization of ER-mitochondria contact sites using cryo-CLEM
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927621006255
Abstract: Several vital physiological processes, such as phospholipid and Ca2+ exchange, mitochondrial biogenesis, autophagy, and intracellular trafficking rely on the contact sites between the endoplasmic reticulum and mitochondria (Kornmann et al., 2009; Hirabayashi et al., 2017).… read more here.
Keywords: microscopy; mitochondria contact; cryo; using cryo ... See more keywords
Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-12382-4
Abstract: Mitochondrial Rho (Miro) GTPases localize to the outer mitochondrial membrane and are essential machinery for the regulated trafficking of mitochondria to defined subcellular locations. However, their sub-mitochondrial localization and relationship with other critical mitochondrial complexes… read more here.
Keywords: microscopy; contact sites; miro; organization ... See more keywords
ER-mitochondria contact sites; a multifaceted factory for Ca2+ signaling and lipid transport
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.988014
Abstract: Membrane contact sites (MCS) between organelles of eukaryotic cells provide structural integrity and promote organelle homeostasis by facilitating intracellular signaling, exchange of ions, metabolites and lipids and membrane dynamics. Cataloguing MCS revolutionized our understanding of… read more here.
Keywords: contact sites; sites multifaceted; multifaceted factory; mitochondria contact ... See more keywords
The Interplay of Microtubules with Mitochondria–ER Contact Sites (MERCs) in Glioblastoma
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DOI: 10.3390/biom12040567
Abstract: Gliomas are heterogeneous neoplasms, classified into grade I to IV according to their malignancy and the presence of specific histological/molecular hallmarks. The higher grade of glioma is known as glioblastoma (GB). Although progress has been… read more here.
Keywords: contact sites; grade; sites mercs; mitochondria contact ... See more keywords