LRRC8A potentiates temozolomide sensitivity in glioma cells via activating mitochondria-dependent apoptotic pathway
Sign Up to like & getrecommendations! Published in 2018 at "Human Cell"
DOI: 10.1007/s13577-018-0221-2
Abstract: Chloride (Cl−), a primary anion in the extracellular fluid, plays an important role in a variety of physiological and pathological processes, such as cell apoptosis and proliferation. However, the information about Cl− in cancer cell… read more here.
Keywords: u87 cells; apoptosis; lrrc8a; mitochondria dependent ... See more keywords
Apigenin attenuates pulmonary hypertension by inducing mitochondria-dependent apoptosis of PASMCs via inhibiting the hypoxia inducible factor 1α-KV1.5 channel pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2020.108942
Abstract: Pulmonary hypertension (PH) is distal pulmonary arterial remodelling and is mainly due to the abnormal proliferation and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs). Apigenin, a natural dietary flavonoid, is a promising PH… read more here.
Keywords: pulmonary hypertension; pasmcs; apoptosis; mitochondria dependent ... See more keywords
Perfluorooctane sulphonate induces oxidative hepatic damage via mitochondria-dependent and NF-κB/TNF-α-mediated pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.08.070
Abstract: Perfluorooctane sulphonate (PFOS) has been reported to accumulate in liver and cause damage. The molecular mechanism of the PFOS-induced hepatotoxicity has not been completely elucidated. The aim of the present study was to investigate whether… read more here.
Keywords: perfluorooctane sulphonate; pfos induced; mitochondria dependent; pfos ... See more keywords
Calreticulin regulated intrinsic apoptosis through mitochondria-dependent and independent pathways mediated by ER stress in arsenite exposed HT-22 cells.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126466
Abstract: Arsenic is a naturally occurring environmental toxicant. Chronic exposure to arsenic is linked with neurological damage. Although the mechanisms remain to be elucidated, it is currently believed that neural cell apoptosis is one of the… read more here.
Keywords: apoptosis; mitochondria dependent; exposure; stress ... See more keywords
Mitochondria-dependent benzothiadiazole-based molecule probe for quantitatively intracellular pH imaging
Sign Up to like & getrecommendations! Published in 2017 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2017.06.039
Abstract: Abstract In this work, we reported two new pH-sensitive benzothiadiazole-pyridine compounds 1 and 2, which distinctly showed the red-shifted absorption and “turn-off” fluorescence responses to increased pH in a broad range (pH = 2–12). Because of excllent… read more here.
Keywords: live cell; probe; fluorescence; mitochondria dependent ... See more keywords
Hepatocyte growth factor protects pulmonary endothelial barrier against oxidative stress and mitochondria-dependent apoptosis
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001916
Abstract: Abstract Background: Pulmonary microvascular endothelial cells (PMVECs) were not complex, and the endothelial barrier was destroyed in the pathogenesis progress of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). Previous studies have demonstrated that hepatocyte… read more here.
Keywords: dependent apoptosis; stress mitochondria; apoptosis; mitochondria dependent ... See more keywords
Asiatic Acid Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting the ROS-Mediated Mitochondria-Dependent Apoptosis Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3267450
Abstract: Myocardial ischemia-reperfusion injury (MIRI) is a major cause of heart failure in patients with coronary heart disease (CHD). Mitochondrial dysfunction is the crucial factor of MIRI; oxidative stress caused by mitochondrial reactive oxygen species (ROS)… read more here.
Keywords: dependent apoptosis; mitochondria dependent; reperfusion; medicine ... See more keywords
Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity.
Sign Up to like & getrecommendations! Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.132747
Abstract: Doxorubicin (DOX), a chemotherapeutic agent, induces a cardiotoxicity referred to as doxorubicin-induced cardiomyopathy (DIC). This cardiotoxicity often limits chemotherapy for malignancies and is associated with poor prognosis. However, the molecular mechanism underlying this cardiotoxicity is… read more here.
Keywords: dependent ferroptosis; mitochondria dependent; ferroptosis; cardiotoxicity ... See more keywords
Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity
Sign Up to like & getrecommendations! Published in 2023 at "JCI Insight"
DOI: 10.1172/jci.insight.169756
Abstract: , leading to mitochondria-dependent ferroptosis; we also show that mitochondria-dependent ferroptosis is a major cause of DOX cardiotoxicity. In DIC mice, the left ventricular ejection fraction was significantly impaired, and fibrosis and TUNEL + cells… read more here.
Keywords: dox; mitochondria dependent; cardiotoxicity; dependent ferroptosis ... See more keywords
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.962154
Abstract: Polycystic ovary syndrome (PCOS) is a universal endocrine and metabolic disorder prevalent in reproductive aged women. PCOS is often accompanied with insulin resistance (IR) which is an essential pathological factor. Although there is no known… read more here.
Keywords: dependent apoptosis; group pcos; mitochondria dependent; group ... See more keywords