Mitochondria in Huntington’s disease: implications in pathogenesis and mitochondrial-targeted therapeutic strategies
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DOI: 10.4103/1673-5374.360289
Abstract: Huntington’s disease is a genetic disease caused by expanded CAG repeats on exon 1 of the huntingtin gene located on chromosome 4. Compelling evidence implicates impaired mitochondrial energetics, altered mitochondrial biogenesis and quality control, disturbed… read more here.
Keywords: therapeutic strategies; huntington disease; disease; mitochondria huntington ... See more keywords