Chameleon-Like Fluorescent Probe for Monitoring Interplays between Three Organelles and Reporting Cell Damage Processes through Dramatic Color Change.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205026
Abstract: The in-depth study of the interplay and cooperation between multiple organelles is an important biological task. Single fluorescent probes for separate visualization of multiple organelles is a desirable molecular tool, but the construction of such… read more here.
Keywords: three organelles; cell; damage; fluorescent probe ... See more keywords
Mechanism for ginkgolic acid (15 : 1)-induced MDCK cell necrosis: Mitochondria and lysosomes damages and cell cycle arrest.
Sign Up to like & getrecommendations! Published in 2017 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(17)30058-4
Abstract: Ginkgolic acids (GAs), primarily found in the leaves, nuts, and testa of ginkgo biloba, have been identified with suspected allergenic, genotoxic and cytotoxic properties. However, little information is available about GAs toxicity in kidneys and… read more here.
Keywords: cycle arrest; mdck; mitochondria lysosomes; cell cycle ... See more keywords
A series of mitochondria/lysosomes self-targetable near-infrared hemicyanine dyes for viscosity detection.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c00054
Abstract: Six mitochondria/lysosomes self-targetable and viscosity-sensitive dyes (1a-f) were developed via simple structure modification on cyanine-derived dyes. They all showed remarkable OFF-ON fluorescent response to viscosity in near-infrared region (652-690 nm) and exhibited good linear relationship… read more here.
Keywords: viscosity; mitochondria lysosomes; near infrared; series mitochondria ... See more keywords
One Stone, Three Birds: A Smart Single Fluorescent Probe for Simultaneous and Discriminative Imaging of Lysosomes, Lipid Droplets, and Mitochondria.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03073
Abstract: Complex intracellular life processes are usually completed through the cooperation of multiple organelles. Real-time tracking of the interplays between multiple organelles with a single fluorescent probe (SFP) is very helpful to deepen our understanding of… read more here.
Keywords: single fluorescent; lipid droplets; fluorescent probe; mitochondria lysosomes ... See more keywords
Fluorescence Lifetime-Resolved Ion-Selective Nanospheres for Simultaneous Imaging of Calcium Ion in Mitochondria and Lysosomes.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b00735
Abstract: In this paper, novel calcium-selective nanospheres incorporating Pluronic F127 and (4-carboxybutyl) triphenylphosphonium bromide (TPP) as shell layers were designed to monitor the level of free calcium ion in mitochondria and lysosomes at living cells simultaneously.… read more here.
Keywords: mitochondria lysosomes; fluorescence; selective nanospheres; ion ... See more keywords
Parallel damage in mitochondria and lysosomes is an efficient way to photoinduce cell death
Sign Up to like & getrecommendations! Published in 2018 at "Autophagy"
DOI: 10.1080/15548627.2018.1515609
Abstract: ABSTRACT Cells challenged by photosensitized oxidations face strong redox stresses and rely on autophagy to either survive or die. However, the use of macroautophagy/autophagy to improve the efficiency of photosensitizers, in terms of inducing cell… read more here.
Keywords: parallel damage; cell death; mitochondria lysosomes; damage ... See more keywords
The regulatory mechanism between lysosomes and mitochondria in the aetiology of cardiovascular diseases
Sign Up to like & getrecommendations! Published in 2022 at "Acta Physiologica"
DOI: 10.1111/apha.13757
Abstract: Coordinated action among various organelles maintains cellular functions. For instance, mitochondria and lysosomes are the main organelles contributing to cellular metabolism and provide energy for cardiomyocyte contraction. They also provide essential signalling platforms in the… read more here.
Keywords: mitochondria aetiology; cardiovascular diseases; mechanism lysosomes; lysosomes mitochondria ... See more keywords
Label-free dynamic imaging of mitochondria and lysosomes within living cells via simultaneous dual-pump photothermal microscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Biomedical optics express"
DOI: 10.1364/boe.10.005852
Abstract: The dynamic activities of mitochondria and lysosomes, which play important roles in maintaining cellular homeostasis, were observed without labeling by using highly sensitive photothermal (PT) microscopy. This imaging modality allows for the direct observation of… read more here.
Keywords: mitochondria lysosomes; microscopy; photothermal microscopy; via simultaneous ... See more keywords
Fluorescent Probes Design Strategies for Imaging Mitochondria and Lysosomes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.915609
Abstract: Modern cellular biology faces several major obstacles, such as the determination of the concentration of active sites corresponding to chemical substances. In recent years, the popular small-molecule fluorescent probes have completely changed the understanding of… read more here.
Keywords: design strategies; fluorescent probes; strategies imaging; probes design ... See more keywords