Mitochondria, mitophagy, and the role of deubiquitinases as novel therapeutic targets in liver pathology
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30312
Abstract: Liver diseases such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), fibrosis, and hepatocellular carcinoma (HCC) have increased over the past few decades due to the absence or ineffective therapeutics. Recently, it has been… read more here.
Keywords: mitochondria mitophagy; role deubiquitinases; mitophagy role; role ... See more keywords
Actin cages isolate damaged mitochondria during mitophagy
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DOI: 10.1080/15548627.2018.1486152
Abstract: ABSTRACT Mitochondrial homeostasis is maintained by removing dysfunctional, ubiquitinated mitochondria from the network via PRKN-dependent mitophagy. MYO6, a unique myosin that moves towards the minus ends of actin filaments, forms a complex with PRKN and… read more here.
Keywords: mitochondria mitophagy; damaged mitochondria; isolate damaged; actin cages ... See more keywords
Structural and Dynamic Features of Liver Mitochondria and Mitophagy in Rats with Hyperthyroidism
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214327
Abstract: This work investigated the effect of thyroxine on the biogenesis and quality control system of rat liver mitochondria. Chronic administration of thyroxine to experimental animals induced hyperthyroidism, which was confirmed by a severalfold increase in… read more here.
Keywords: mitochondria mitophagy; liver mitochondria; features liver; thyroxine ... See more keywords