Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Nature immunology"
DOI: 10.1038/s41590-021-01065-2
Abstract: Misdirected immunity gives rise to the autoimmune tissue inflammation of rheumatoid arthritis, in which excess production of the cytokine tumor necrosis factor (TNF) is a central pathogenic event. Mechanisms underlying the breakdown of self-tolerance are… read more here.
Keywords: mitochondrial aspartate; aspartate; autoimmune; tissue inflammation ... See more keywords