Association of Mitochondrial Biogenesis With Variable Penetrance of Schizophrenia.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2021.0762
Abstract: Importance Discovery of mechanisms that underlie variable penetrance for neuropsychiatric illness in the context of genetic variants that carry elevated risk can advance novel treatment approaches for these disorders. Objective To test the hypothesis that… read more here.
Keywords: variable penetrance; 22q group; mitochondrial biogenesis; schizophrenia ... See more keywords
Ameliorating Mitochondrial Dysfunction of Neurons by Biomimetic Targeting Nanoparticles Mediated Mitochondrial Biogenesis to Boost the Therapy of Parkinson's Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300758
Abstract: Mitochondrial dysfunction of neurons is the core pathogenesis of incurable Parkinson's disease (PD). It is crucial to ameliorate the mitochondrial dysfunction of neurons for boosting the therapy of PD. Herein, the remarkable promotion of mitochondrial… read more here.
Keywords: mitochondrial biogenesis; parkinson disease; dysfunction neurons; mitochondrial dysfunction ... See more keywords
Mitochondrial biogenesis in neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24042
Abstract: Mitochondria play a key role in energy production, calcium homeostasis, cell survival, and death. Adverse stimulations including neurodegenerative diseases may result in mitochondrial dynamic imbalance, free radical production, calcium accumulation, intrinsic cell death pathway activation… read more here.
Keywords: mitochondrial biogenesis; death; biogenesis neurodegeneration; pgc ... See more keywords
Effect of dietary resveratrol supplementation on meat quality, muscle antioxidative capacity and mitochondrial biogenesis of broilers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.8576
Abstract: BACKGROUND The naturally occurring polyphenol resveratrol has been acknowledged with many beneficial biological effects. The aim of this study was to evaluate the influence of dietary resveratrol supplementation on meat quality, muscle antioxidative capacity and… read more here.
Keywords: antioxidative capacity; resveratrol; mitochondrial biogenesis; meat quality ... See more keywords
Nickel induces hepatotoxicity by mitochondrial biogenesis, mitochondrial dynamics, and mitophagy dysfunction
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23758
Abstract: Nickel (Ni) is an important and widely hazardous chemical industrial waste. Excessive Ni exposure could cause multi‐organs toxicity in human and animals. Liver is the major target organ of Ni accumulation and toxicity, however, the… read more here.
Keywords: nickel; biogenesis mitochondrial; mitochondrial biogenesis; biogenesis ... See more keywords
Mitochondrial Biogenesis, Activity, and DNA Isolation in Chondrocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1119-7_14
Abstract: Chondrocytes, the only cells in articular cartilage, are metabolically active and responsible for the turnover of extracellular matrix and maintenance of the tissue homeostasis. Changes in chondrocyte function can cause degradation of the matrix and… read more here.
Keywords: biogenesis activity; mitochondrial biogenesis; activity dna;
Ochratoxin A causes mitochondrial dysfunction, apoptotic and autophagic cell death and also induces mitochondrial biogenesis in human gastric epithelium cells
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02433-6
Abstract: Ochratoxin A (OTA) is a common natural contaminant found in human and animal food worldwide. Our previous work has shown that OTA can cause oxidative DNA damage, G2 arrest and malignant transformation of human gastric… read more here.
Keywords: mitochondrial biogenesis; death also; cell death; autophagic cell ... See more keywords
Training and acute exercise modulates mitochondrial dynamics in football players’ blood mononuclear cells
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Applied Physiology"
DOI: 10.1007/s00421-017-3684-z
Abstract: PurposeRegular physical activity induces oxidative stress but also causes adaptations in antioxidant defences including the nuclear factor κB (NF-κB) pathway, which activates target genes related to antioxidant defences such as uncoupling proteins (UCPs), and mitochondrial… read more here.
Keywords: mitochondrial biogenesis; football players; training acute; acute exercise ... See more keywords
Effect of cholestasis and NeuroAid treatment on the expression of Bax, Bcl-2, Pgc-1α and Tfam genes involved in apoptosis and mitochondrial biogenesis in the striatum of male rats
Sign Up to like & getrecommendations! Published in 2019 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-019-00508-y
Abstract: Cholestasis means impaired bile synthesis or secretion. In fact, it is a bile flow reduction following Bile Duct Ligation (BDL). Cholestasis has a main role in necrosis and apoptosis. Apoptosis is a form of programmed… read more here.
Keywords: mitochondrial biogenesis; expression bax; effect; expression ... See more keywords
A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2588-6
Abstract: A ketogenic diet (KD; high-fat, low-carbohydrate) can benefit refractory epilepsy, but underlying mechanisms are unknown. We used mice inducibly expressing a mutated form of the mitochondrial DNA repair enzyme UNG1 (mutUNG1) to cause progressive mitochondrial… read more here.
Keywords: pgc1 sirt3; mitochondrial biogenesis; sirt3 ucp2; mutung1 mice ... See more keywords
Ginkgo biloba mitigates silver nanoparticles-induced hepatotoxicity in Wistar rats via improvement of mitochondrial biogenesis and antioxidant status
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-019-05835-2
Abstract: Silver nanoparticles (AgNPs) are noble metal nanoparticles, due to their good physicochemical properties, which have been exploited in biological applications. Nanotechnological applications advance very quickly while few literatures assessed the effects of natural products on… read more here.
Keywords: status; mitochondrial biogenesis; silver nanoparticles; induced hepatotoxicity ... See more keywords