The nature compound dehydrocrenatidine exerts potent antihepatocellular carcinoma by destroying mitochondrial complexes in vitro and in vivo
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DOI: 10.1002/ptr.7398
Abstract: Cumulative evidence indicates that mitochondria dysfunction plays an important role in tumour treatment. Given the limited efficacy and toxicity of current mitochondria‐targeted drugs, research into effective mitochondria‐targeted anticancer agents remains an irresistible general trend. In… read more here.
Keywords: vitro vivo; compound; mitochondrial complexes; dec ... See more keywords
Molecular Signatures of Mitochondrial Complexes Involved in Alzheimer's Disease via Oxidative Phosphorylation and Retrograde Endocannabinoid Signaling Pathways
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DOI: 10.1155/2022/9565545
Abstract: Objective The inability to intervene in Alzheimer's disease (AD) forces the search for promising gene-targeted therapies. This study was aimed at exploring molecular signatures and mechanistic pathways to improve the diagnosis and treatment of AD.… read more here.
Keywords: mitochondrial complexes; hub; oxidative phosphorylation; molecular signatures ... See more keywords